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Tag Archives | SSRI

Minimal Effects of Prenatal SSRIs on Motor Development in Exposed Children

When we meet with women to discuss the reproductive safety of antidepressant medications, one of the most challenging and anxiety-provoking aspects of the consultation is the discussion we have regarding the long-term effects of prenatal antidepressant exposure on the child.  Because studies assessing the effects of prenatal exposure to medication (or other environmental exposures) take […]

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Risk of Neonatal Morbidity in Infants Exposed to SSRIs

A few days ago, an article was published in the journal Pediatrics on neonatal morbidity observed in children exposed to antidepressants.  Although this article is likely to find its way into the headlines, it is important to note that the information presented here is nothing new.  Similar to previous studies, the Pediatrics study reveals higher […]

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Prenatal SSRI Exposure and Speech/Language Disorders: Many Headlines, Little Risk

Last week, an article looking at the cognitive and motor development of children with prenatal exposure to antidepressants was published in JAMA Psychiatry.  Since that time, we have received a lot of questions regarding the article and the clinical implications of its findings.  When I did a quick Google search, I found 36 articles reviewing […]

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Credit: Pregnant Woman from Wikimedia Commons

Antidepressants and Postpartum Hemorrhage: No Risk with SSRIs, Small Risk with SNRIs

Serotonin reuptake inhibitor (SRI) antidepressants may affect platelet aggregation and thus may increase the risk of bleeding.  Several studies have sought to determine if exposure to SSRI antidepressants in late pregnancy is associated with an increased risk of postpartum hemorrhage. The most recent study was a population-based cohort study including 225,973 women with a total […]

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Baby Belly from Wikimedia Commons

SSRIs and Pregnancy: No Risk of Cardiovascular Malformations According to UK Study

Over the last few years, several studies have suggested an increased risk of certain types of cardiovascular malformations in children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The first reports suggested a link between cardiac septal defects and exposure to paroxetine; other, but not all, studies have also shown an elevated risk of […]

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Postpartum Hemorrhage in Women Taking Antidepressants During Pregnancy

Serotonin reuptake inhibitor (SRI) antidepressants may affect platelet aggregation and thus may increase the risk of bleeding.  Several studies have sought to determine if exposure to SSRI antidepressants in late pregnancy is associated with an increased risk of postpartum hemorrhage. The most recent study comes from Australia and analyzes risk for postpartum hemorrhage in a […]

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Credit: Pregnant Woman from Wikimedia Commons

Taking A Closer Look: Autism and Antidepressants

Earlier this week, JAMA Pediatrics released the findings of a study which suggested that prenatal exposure to antidepressants may increase the risk of autism spectrum disorders (ASDs). Not surprisingly, this has created a considerable amount of anxiety among women taking these medications.  While the headlines may prompt women and their treaters to avoid these medications, […]

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Credit: Depressed Mother from Wikimedia Commons

Antidepressant Effects on Motor Development Minimal, According to New Study

When we meet with women to discuss the reproductive safety of antidepressant medications, one of the most challenging and anxiety-provoking aspects of the consultation is the discussion we have regarding the long-term effects of prenatal antidepressant exposure on the child.  Does antidepressant exposure during the earliest stages of brain development have lasting effects? Because studies […]

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PMDD and Serotonin Reuptake Inhibitors: Does Symptom-Onset Dosing Work?

Multiple studies support the efficacy of serotonin reuptake inhibitors (SRIs) for the treatment of premenstrual dysphoric disorder (PMDD).  In the initial studies, treatment was administered daily throughout the entire menstrual cycle.  Researchers observed that for the treatment of PMDD, SRIs seemed to work more rapidly, taking effect within a few days of treatment initiation (as […]

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In Brief: Venlafaxine as Effective as Low-Dose Estradiol for Menopausal Sleep Symptoms

Which treatment is best for managing menopausal sleep problems? We tend to think of estrogen replacement therapy as being the best option for all menopausal symptoms; however, there are other options for managing menopausal symptoms, including serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors, and gabapentin. A recent study compares low-dose estradiol and low-dose venlafaxine for the […]

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