Clinical Update 2026: Z-Drugs and Pregnancy
Recent studies find no increase in the risk of major malformations with first-trimester Z-drug exposure, although small increases in risk of preterm birth and low birth weight have been reported.
Recent studies find no increase in the risk of major malformations with first-trimester Z-drug exposure, although small increases in risk of preterm birth and low birth weight have been reported.
In this multicenter cohort, maternal cannabis use documented using urine drug sampling was associated with increased risk of adverse pregnancy outcomes related to placental dysfunction.
Lithium use during pregnancy was associated with an increased risk of preterm birth and large for gestational age infants.
Prenatal cannabis exposure was associated with persisting vulnerability to psychopathology throughout early adolescence.
The findings of this study do not suggest that prenatal antipsychotics exposure is associated with increased risk for ADHD, ASD, small for gestational age, or preterm birth.
Heavy cannabis use during pregnancy was associated with increased risk for small for gestational age, preterm birth, low birth weight, and death during the first year of life.
Gabapentin (Neurontin) is now used in a wide variety of clinical settings — for the treatment of epilepsy, pain management, restless leg syndrome, anxiety, and sleep disturbance. However, there is relatively little information regarding [...]
When providing information to patients regarding the use of medications during pregnancy, one key element of the decision-making process is an appraisal of the risks associated with untreated psychiatric illness in the mother. While there [...]
Most studies have shown that women experience an improvement or remission in eating disorders during pregnancy; however, studies assessing how eating disorders may affect pregnancy outcomes have yielded conflicting results. While some studies have demonstrated no negative effects, others have demonstrated higher miscarriage rates among women with bulimia nervosa. In addition, women with histories of eating disorders have been shown to be significantly more likely to experience preterm delivery and to give birth to babies small for gestational age.