For women who require treatment with quetiapine during pregnancy, the available reproductive safety data are generally reassuring. The largest body of evidence does not suggest a meaningful increase in major congenital malformations, while metabolic effects, particularly gestational diabetes, remain an important consideration.
The current study observed no significant differences in overall developmental outcomes or behavior in exposed versus unexposed children.
Lithium use during pregnancy was associated with an increased risk of preterm birth and large for gestational age infants.
Prenatal cannabis exposure was associated with persisting vulnerability to psychopathology throughout early adolescence.
The findings of this study do not suggest that prenatal antipsychotics exposure is associated with increased risk for ADHD, ASD, small for gestational age, or preterm birth.
Heavy cannabis use during pregnancy was associated with increased risk for small for gestational age, preterm birth, low birth weight, and death during the first year of life.
The use of the newer “atypical” or second-generation antipsychotic (SGA) agents continues to increase. These medications are used to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and anxiety disorders. [...]
