reproductive safety

Risk of Preterm Birth and Respiratory Distress in Pregnancies with Prenatal Exposure to Antidepressants

From the OptumLabs Data Warehouse, researchers identified 226,932 singleton deliveries. Cases of antidepressant exposure were defined as pregnancies with prescription claims for antidepressants submitted between the last menstrual period and 35 weeks’ gestation.  To [...]

No Increased Risk of Autism in Children Prenatally Exposed to Commonly Used Antidepressants

Concerns regarding a link between antidepressant use during pregnancy and autism emerged when two epidemiologic studies demonstrated an association between prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) with an increased risk of autism [...]

Good News: More Data on the Use of ADHD Medications During Pregnancy

For women with mild to moderate attention-deficit/hyperactivity disorder (ADHD) symptoms, we often recommend discontinuing stimulant medications and switching to a non-pharmacologic intervention.  Many women experience some decrease in their level of functioning; however, they are [...]

Is It Safe During Pregnancy? There’s An App for That

  January was Birth Defects Prevention Month, and MotherToBaby launched a free app  designed to provide evidence-based information to pregnant and breastfeeding women. There is Information on a broad range of medications, some herbal remedies, [...]

New Research from the CWMH: Evaluating the Risk of Major Malformations in Children Prenatally Exposed to Atypical Antipsychotics

Despite the increasing use of the newer “atypical” or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little data [...]