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Tag Archives | pregnancy

Fetal Alcohol Disorders More Common Tnan Previously Thought

Fetal Alcohol Spectrum Disorder (FASD) refers to a constellation of disorders resulting from prenatal exposure to alcohol; the manifestations include birth defects, developmental disabilities, and neurological and behavioral problems. Prenatal alcohol exposure is the most common preventable cause of birth defects, and fetal alcohol spectrum disorders are the most commonly identifiable causes of developmental delays […]

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Prescribing Psychotropic Medications with Opioids During Pregnancy May Increase Risk for Neonatal Withdrawal

  Illicit opioid use has steadily increased over the past decade, and this increase is most prominent in the 18–25 age group, which includes women of reproductive age (Substance Abuse and Mental Health Services Administration, 2013). Paralleling this increase in illicit opiate use in this population has been a significant increase in the use of […]

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Is Psychiatric Illness a Risk Factor for Hyperemesis Gravidarum?

  While the majority of pregnant women experience nausea and/or vomiting during the first trimester of pregnancy, a smaller subset of women — around 1% — experience more severe and intractable vomiting, or hyperemesis gravidarum (HG).  If left untreated, prolonged hyperemesis can lead to weight loss, dehydration, nutrient deficiencies and electrolyte disturbances.   We do […]

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Lamotrigine and Pregnancy: Meta-Analysis Shows No Increase in Risk for Malformations

  Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly used in this setting, including lithium and valproic acid, carry some degree of teratogenic risk. In contrast, lamotrigine (Lamictal) appears to be a much safer option for […]

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In Brief: Beta Blockers and Pregnancy, No Observed Increase in Risk of Malformations

Beta blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women.  They are also effective for the treatment of anxiety symptoms, most commonly performance anxiety. According to a report published online in JAMA Internal Medicine, maternal use of beta-blockers during pregnancy (n=4847) was associated with increased risk for fetal […]

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More Data on Pregabalin (Lyrica) and Pregnancy

Pregabalin (marketed in the US as Lyrica) is approved by the US Food and Drug Administration for the treatment of epilepsy, fibromyalgia, and neuropathic pain.  It is also used off-label to treat psychiatric disorders, most commonly generalized anxiety disorder.  While it is not used as frequently as other anti-epileptic drugs, we do occasionally see women […]

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Is BDNF a Biomarker for Depression During Pregnancy and the Postpartum Period?

Brain-derived neurotrophic factor (BDNF) is a growth factor which acts on neurons in both the central and peripheral nervous systems, promoting the survival of neurons and promoting the growth and differentiation of new neurons and synapses.  In the brain, it is most active in the hippocampus, cortex, and basal forebrain—areas important  to learning, memory, and […]

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USPSTF Emphasizes Periconceptual Use of Folic Acid to Prevent Birth Defects

Neural tube defects are among the most common major congenital anomalies in the United States and are associated with significant disability and death.  The risk of neural tube defects can be prevented with daily folic acid supplementation in the periconceptional period.  However, most women do not receive the recommended daily intake of folate.  January 5–11 […]

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Credit: Pregnant Woman from Wikimedia Commons

The 50-year Quest for Better Pregnancy Data

The following post was first published in OB/GYN News. Please see our OB/GYN News archives here. Publish date: November 1, 2016 By: Gerald G. Briggs, BPharm, FCCP, Christina Chambers, PhD, MPH, Lee S. Cohen, MD, & Gideon Koren, MD Editor’s note: As Ob.Gyn. News celebrates its 50th anniversary, we wanted to know how far the medical community has come in identifying and […]

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MCPAP for Moms: Exploring New Strategies for Providing Care to Women with Perinatal Depression

We are clearly making big strides in terms of increasing public awareness of perinatal mood and anxiety disorders, but we still have a long way to go when it comes to providing access to mental health professionals with expertise in this area.  We have demonstrated that screening for perinatal depression can be carried out successfully […]

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