Clinical Update 2025: Recommendations on the Use of Antidepressants in Women Taking Tamoxifen
While some antidepressants may affect the metabolism of tamoxifen into its active form, many antidepressants can be used safely in this population.
Impact of Antidepressants on Male Fertility: New Data on Duloxetine
The current study indicates that duloxetine administered at a dose of 60 mg does not have an impact on sperm quality.
Clinical Update 2019: Tamoxifen and Antidepressants
Women receiving tamoxifen for the treatment or prevention of breast cancer should be aware of possible drug-drug interactions between tamoxifen and specific antidepressant medications. Antidepressants are used widely to treat depression and anxiety disorders in [...]
Combining Tamoxifen with Antidepressants: What You Need to Know
An updated version of this post can be found HERE. Two thirds of all breast cancer tumors are known to have receptors that respond to hormones; that is they can grow in response to estrogen. [...]
SSRIs and Pregnancy: No Risk of Cardiovascular Malformations According to UK Study
Over the last few years, several studies have suggested an increased risk of certain types of cardiovascular malformations in children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The first reports suggested a link [...]
More Data on the Interaction Between Antidepressants and Tamoxifen
An updated version of this post can be found HERE. Tamoxifen is a selective estrogen receptor modulator (or SERM) which is used for the treatment and prevention of breast cancer. Tamoxifen’s effects in the breast [...]
Antidepressants and Pregnancy: Are Some SSRIs Safer Than Others?
 Over the last decade, numerous studies on the reproductive safety of selective serotonin reuptake inhibitors (SSRIs) have been published.  However, these studies, using different methodologies and studying different populations, have often yielded conflicting results. [...]
SSRIs and Pregnancy: No Increase in Risk of Malformations
Over the last few years, we have reported on several studies which have suggested an increased risk of certain types of cardiovascular malformations among children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The first reports [...]
Low Dose Paroxetine Improves Sleep in Postmenopausal Symptoms
Last year, the FDA approved the first non-hormonal treatment for hot flashes – a 7.5-mg formulation of the selective serotonin reuptake inhibitor (SSRI) paroxetine which was marketed under the name of Brisdelle. A new study [...]
SSRI Antidepressants Not Associated with Cardiovascular Defects
Over the last few years, we have reported on several studies which have suggested an increased risk of certain types of cardiovascular malformations among children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The [...]