OC

You Asked: Is There an Interaction Between Lamotrigine and Oral Contraceptives?

We get many questions about the interaction between lamotrigine (Lamictal) and oral contraceptives (OCs). While many readers raise concerns that lamotrigine may decrease the effectiveness of oral contraceptives, the primary interaction is actually in [...]

By Ruta Nonacs, MD PhD|2025-06-26T09:07:06-04:00September 29th, 2015|You Asked|Comments Off

Clinical Update: Use of Topiramate (Topamax) During Pregnancy

Topiramate (TPM, marketed as Topamax) is an antiepileptic drug which is also used for migraine prophylaxis, weight loss, and, less commonly, as a mood stabilizer. Over the last few years we have seen several studies suggesting an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy. You can read more about those studies here:

By MGH Center for Women's Mental Health|2015-05-25T20:50:06-04:00February 2nd, 2015|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off