In women, testosterone is produced by the ovaries in small amounts; however, levels of testosterone decline with age, independent of menopausal status. Low-dose testosterone has been used to improve sexual functioning in women with hypoactive [...]
Over the last few years we have heard a great deal about neurosteroids, also known as neuroactive steroids. This class of compounds are steroid hormones produced in the brain and endocrine tissues which can [...]
Patients and clinicians may not be fully aware that women are at increased risk for depression during the menopausal transition. The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians screen all adults for [...]
Recent studies suggest that the burden of menopausal symptoms is greater than generally perceived. About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the [...]
In our clinic, we often see women with symptoms of depression and anxiety which emerge in the context of the menopausal transition; many of these women have suffered for years with severe symptoms before [...]
A growing body of research indicates that the menopausal transition is a period of increased vulnerability to depressive illness. Some women have experienced episodes of major depressive disorder (MDD) earlier in life and experience recurrent [...]
Here's a new way to look at hot flashes. How much do they cost our society in terms of additional health care and lost productivity?
Hot flashes and depression are both common symptoms of the menopause transition. Several studies have found a relationship between depression and hot flashes: depressed women are more likely to experience hot flashes and women with hot flashes are more likely to have depression. Other studies have found no association between hot flashes and depression.
It is well established that women are at increased risk for developing depression compared to men. It has been hypothesized that this vulnerability to depression may be hormonally mediated, and several longitudinal studies have documented an increased risk of depressive symptoms during perimenopause or the menopausal transition. Based on the results of two prospective cohort studies, approximately one-third of women will develop their first episode of depression during the menopausal transition. (Cohen LS et al 2006, Freeman EW et al 2006).