• MDD

    Is Postpartum Depression a Distinct Subtype of Depression? Taking a Closer Look at the Amygdala

    While many women with postpartum depression (PPD) have had previous episodes of major depression and will go on to have other episodes of depression outside of the postpartum period, many have questioned whether postpartum depression [...]

    Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

    In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]

    Screening for Depression During Pregnancy May Lead to Misdiagnosis for Women with Bipolar Disorder

    The American College of Obstetrics and Gynecology now recommends that women be screened for depression during pregnancy.  Because depressive symptoms during pregnancy have been associated with worse outcomes and are a robust predictor of postpartum [...]

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