Essential Reads: Topiramate and Pregnancy (2021)
Multiple studies have associated first trimester exposure to topiramate with increased risk of oral clefts.
New Research from the CWMH: No Increase in Major Malformations in Children Prenatally Exposed to Aripiprazole
Despite the increasing use of the newer atypical or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including psychotic disorders, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little [...]
Prescription Opioids During Pregnancy and Risk for Major Malformations
Previous studies have suggested a link between opioid exposure during pregnancy and increased risk of certain major malformations, including neural tube defects. A recent study from Bateman and colleagues assesses the risk of major malformation [...]
Essential Reads: Mirtazapine (Remeron) and Pregnancy
This is the first installment of a new feature on our website: ESSENTIAL READS This is a kind of shortcut which allows you to find the most relevant reviews and articles in reproductive psychiatry. [...]
Modafinil and Armodafinil During Pregnancy: Data to Suggest Increased Risk of Malformations
As soon as we published this article on the use of modafinil during pregnancy, another study was published which included data on the reproductive safety of modafinil and armodafinil from the US Provigil/Nuvigil Pregnancy [...]
Assessing the Reproductive Safety of Antidepressants: Can Non-Randomized Studies Provide the Information We Need?
Perinatal psychiatry is a field in which we treat vulnerable patients, a mother and her child, where both the illness we are treating and the treatments we prescribe have the potential to affect the outcome. [...]
Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy
Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly [...]
Valproic Acid: Highlighting Risk and Modifying Prescribing Patterns in Reproductive Age Women
For clinicians who have not yet discovered the incredibly thoughtful and clinically practical monthly articles from Chittaranjan Andrade in the Journal of Clinical Psychiatry, it’s time to take a look. (Not only are these articles [...]
Lamotrigine and Pregnancy: Meta-Analysis Shows No Increase in Risk for Malformations
Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly used in this setting, including lithium and [...]
Prenatal Antiepileptic Exposure Increases Risk for Malformations: Does High-Dose Folic Acid Reduce Risk?
The CDC, the U.S. Public Health Service, and the American College of Obstetricians and Gynecologists (ACOG) all recommend that every woman of reproductive age get 400 micrograms (400 mcg) or 0.4 milligrams of folic acid [...]