ABCL635 Shows Promise for Menopausal Hot Flashes in Phase 2 Trial
A new nonhormonal treatment targeting the neurokinin 3 receptor significantly reduced the frequency and severity of menopausal hot flashes in a Phase 2 trial.
CBT for Menopause: Improving Sleep and Hot Flashes Without Medication
CBT tailored for menopause may improve insomnia, hot flashes, and mood. New research highlights benefits—and the need for strategies to sustain improvements over time.
Beyond Hot Flashes: The Hidden Toll of Menopausal Sleep Disturbance on Well-Being
Sleep disturbance is common in peri- and postmenopausal women, even in the absence of VMS, and is independently linked to worse quality of life, depression, and anxiety.
Gabapentin: A Non-Hormonal Option for the Treatment of Menopausal Vasomotor Symptoms
Current guidelines list gabapentin as a recommended nonhormonal therapy for vasomotor symptoms in women who cannot or prefer not to use hormone therapy.
Dr. Lee Cohen Discusses Menopause on the It’s Not a Crisis Podcast
In this episode of It’s Not a Crisis, Dr. Lee Cohen speaks with host Doryn Wallach about the struggles many women experience during the menopausal transition. For most women, menopausal symptoms are manageable, but for [...]
CBT Effective for Perimenopausal Vasomotor Symptoms, Sleep and Depression
CBT is effective for the management of vasomotor symptoms, depression, and sleep in perimenopausal women.
New Research from the CWMH: Vortioxetine Effective for Depression and Menopausal Symptoms
As women transition into the menopause, they experience a constellation of symptoms including vasomotor symptoms (hot flashes and night sweats), sleep disruption, problems with sexual functioning, and cognitive impairment. Women may also be more [...]
NT-814: Neurokinin Receptor Antagonist Effective for Menopausal Vasomotor Symptoms
Stimulation of NKB-neurokinin 3 receptor (NK3R) signalling can induce hot flashes
Neurokinin Receptor Antagonists for the Treatment of Menopausal Symptoms
About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase. For most, the symptoms are manageable, but for a sizeable subset of midlife [...]
Menopausal Symptoms More Common in Women with History of Intimate Partner Violence
While we have identified various sociodemographic variables as factors which modulate vulnerability to menopausal symptoms, no studies (to my knowledge) have looked at how a history of intimate partner violence (IPV) or other traumatic exposures [...]