Perimenopausal vasomotor symptoms are triggered by a fall in circulating levels of estrogen and other sex steroids. It has been hypothesized that thermoregulatory centres in the hypothalamus play a crucial role in mediating the hot flash response. However, exactly how do hormonal changes bring about these changes in the hypothalamus? If we could understand this […]
Tag Archives | hot flashes
Since the Women’s Health Initiative (WHI) reported that the risks of menopausal hormone replacement therapy (HRT) outweighed its benefits, there has been a significant reduction in the use of HRT. However, recent studies have suggested that many peri- and postmenopausal women experience significant symptoms for many years and that these symptoms have a marked impact […]
A recent study examined the effectiveness of electroacupuncture, in which small electric currents are applied to traditional acupuncture needles, in women with breast cancer treatment-associated hot flashes. 120 women with hot flashes were randomized to weekly electroacupuncture, once-daily gabapentin, sham acupuncture, or placebo for 8 weeks. Hot flashes were assessed using a daily self-reported hot […]
The menopausal transition is a difficult time for many women. There is an increased risk of depressive episodes during this transition in the reproductive lifecycle, and the majority of women will experience symptoms related to perimenopause (such as hot flashes, sleep disturbance, and cognitive complaints). Vortioxetine (brand name Brintellix) is a novel antidepressant that was […]
Recent research has indicated that selective serotonin reuptake inhibitors (SSRIs) may be an effective option for the treatment of vasomotor symptoms associated with menopause. However, it has been documented in some recent observational studies that SSRIs are associated with an increased risk of bone loss in older patients (2, 4). Since postmenopausal women are already […]
Several recent articles indicate that the burden of menopausal symptoms is greater than generally perceived. About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase. For most, the symptoms are manageable, but for a sizeable subset of midlife women, these symptoms can negatively […]
In healthy perimenopausal women with hot flashes, treatment with both estradiol and venlafaxine resulted in significantly greater improvement in quality of life, as compared to placebo. Estradiol had beneficial treatment effects on all domains of the MENQOL except for the psychosocial domain, whereas venlafaxine benefits were observed only in the psychosocial domain. Caan B, LaCroix […]
Several recent articles suggest that the burden of menopausal symptoms is greater than generally perceived. About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase. For most, the symptoms are manageable, but for a sizeable subset of midlife women, these symptoms can negatively […]
Over the last decade, various studies have evaluated the effectiveness of acupuncture for the treatment of menopausal vasomotor symptoms. In a recent meta-analysis, studies that reported on the frequency or severity of hot flashes, menopause-related symptoms assessed using the Menopause Rating Scale (MRS), and quality of life (QoL) assessed using the Menopause-Specific Quality of Life (MSQoL) questionnaire were included. Twelve studies with a total of 869 participants met the inclusion criteria and were included in the final analysis.
Studies evaluating the relationship of caffeine to vasomotor symptoms have yielded conflicting results.