• estrogen

    New Research from the CWMH: Both Estradiol and Venlafaxine Improve Quality of Life in Perimenopausal Women with Hot Flashes

    In healthy perimenopausal women with hot flashes, treatment with both estradiol and venlafaxine resulted in significantly greater improvement in quality of life, as compared to placebo. Estradiol had beneficial treatment effects on all domains of the [...]

    Hormone Replacement Therapy: Some Risk But No Impact on Mortality

    While there are concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain settings.  A study presented this week at the Endocrine Society’s annual meeting which analyzed data from 43 randomized clinical trials suggests that menopausal hormone-replacement therapy does not appear to affect mortality either positively or negatively.

    Stellate Ganglion Blockade for Vasomotor Symptoms

    A study to be published in an upcoming issue of Menopause suggests that stellate ganglion blockade (SGB) may be an effective option for women with vasomotor symptoms (VMS), including hot flashes and night sweats.  SGB is used primarily for pain management and involves the injection of local anesthetic into the stellate ganglion, part of the sympathetic nerve system located in the neck.

    Progesterone for Hot Flashes

    Following the publication of the Women's Health Initiative report in 2002, there was a dramatic drop in the use of hormone-replacement therapy (HRT) due to concerns about increased risk of heart disease, breast cancer, and stroke.  Since that time, various non-hormonal alternatives have been utilized for the treatment of menopausal symptoms, including gabapentin and various serotonin reuptake inhibitors.

    Go to Top