depression

Modafinil and Armodafinil During Pregnancy: Data to Suggest Increased Risk of Malformations

As soon as we published this article on the use of modafinil during pregnancy, another study was published which included data on the reproductive safety of modafinil and armodafinil from the US Provigil/Nuvigil Pregnancy [...]

By |2022-01-20T18:11:36-04:00November 4th, 2020|ADHD Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Modafinil and Armodafinil During Pregnancy: Data to Suggest Increased Risk of Malformations

Is Postpartum Depression a Distinct Subtype of Depression? Taking a Closer Look at the Amygdala

While many women with postpartum depression (PPD) have had previous episodes of major depression and will go on to have other episodes of depression outside of the postpartum period, many have questioned whether postpartum depression [...]

By |2020-10-05T11:17:54-04:00October 7th, 2020|Postpartum Depression, Postpartum Psychiatric Disorders|Comments Off on Is Postpartum Depression a Distinct Subtype of Depression? Taking a Closer Look at the Amygdala

Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels

Women are at increased risk for depressive symptoms during the menopause transition.  It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience [...]

By |2020-09-15T17:13:14-04:00September 15th, 2020|Menopausal Symptoms|Comments Off on Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels

More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression

While we have heard a lot about brexanolone, marketed by Sage Therapeutics as Zulresso, for the treatment of postpartum depression, an oral version of this novel antidepressant – SAGE 217 or zuranolone – has been [...]

By |2026-03-10T12:50:13-04:00September 14th, 2020|Medication, Postpartum Depression, Postpartum Psychiatric Disorders, Treatment|Comments Off on More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression

New Research Study: Pregnenolone Neurosteroid for the Treatment of Menopausal Depression

Over the last few years we have heard a great deal about neurosteroids, also known as neuroactive steroids.  This class of compounds are steroid hormones produced in the brain and endocrine tissues which can [...]

By |2020-07-27T11:53:51-04:00July 29th, 2020|Depressive Disorders, Menopausal Symptoms, Research at CWMH, Treatment|Comments Off on New Research Study: Pregnenolone Neurosteroid for the Treatment of Menopausal Depression

Recruiting at CWMH: A Neurosteroid Intervention for Menopausal and Perimenopausal Depression

Women are twice as likely as men to have major depressive disorder (MDD) during their lifetimes, and women are particularly at risk during the menopausal transition (including perimenopause and early menopause), which can last [...]

By |2020-08-10T11:20:30-04:00February 19th, 2020|Menopausal Symptoms, Research at CWMH|Comments Off on Recruiting at CWMH: A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
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