cardiac malformations

Lithium Use in Pregnancy and the Risk of Adverse Perinatal Outcomes

A new cohort study from Australia found that lithium use during pregnancy was linked to a two-fold increased risk of spontaneous preterm birth, along with higher risks of a large for gestational age infant and congenital cardiac malformations. We review how these findings compare with prior research and what they mean for women with bipolar disorder who are using — or considering — lithium during pregnancy.

By |2026-09-01T11:34:33-04:00August 19th, 2026|Lithium, Medications and Pregnancy, Mood Stabilizers|Comments Off on Lithium Use in Pregnancy and the Risk of Adverse Perinatal Outcomes

Which is Safer for the Treatment of Opioid Use Disorder During Pregnancy: Buprenorphine or Methadone?

In this large cohort study analyzing data from publicly insured Medicaid beneficiaries, the overall risk of malformations was lower with buprenorphine than with methadone.

By |2024-05-16T06:55:02-04:00March 6th, 2024|Opioids, Perinatal Substance Use, Treatment|Comments Off on Which is Safer for the Treatment of Opioid Use Disorder During Pregnancy: Buprenorphine or Methadone?

New Research from the CWMH: Lithium During Pregnancy and Risk of Cardiovascular Malformations

  While we use lithium less commonly now than we have in the past, lithium is still one of the very best mood stabilizers we have.  And with regard to its reproductive safety, we have [...]

By |2025-06-26T09:07:52-04:00June 19th, 2017|Mood Stabilizers, Outcomes, Pregnancy & Medications, Research at CWMH, Risk of Malformations|Comments Off on New Research from the CWMH: Lithium During Pregnancy and Risk of Cardiovascular Malformations

In Brief: Beta Blockers and Pregnancy, No Observed Increase in Risk of Malformations

Beta blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women.  They are also effective for the treatment of anxiety symptoms, most commonly performance anxiety. According to a report [...]

By |2017-05-04T15:29:30-04:00May 4th, 2017|Anti-Anxiety Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on In Brief: Beta Blockers and Pregnancy, No Observed Increase in Risk of Malformations

Topiramate and Pregnancy: More on Risk of Major Malformations

Topiramate (TPM, marketed as Topamax) is an antiepileptic drug which is also used for migraine prophylaxis, weight loss, and, less commonly, as a mood stabilizer.  Over the last few years we have seen several studies [...]

By |2015-07-07T15:19:19-04:00June 22nd, 2015|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Topiramate and Pregnancy: More on Risk of Major Malformations
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