Clinical Update 2025: Recommendations on the Use of Antidepressants in Women Taking Tamoxifen
While some antidepressants may affect the metabolism of tamoxifen into its active form, many antidepressants can be used safely in this population.
Marlene Freeman, MD: Getting to the Truth About SSRIs and Pregnancy (Video)
The recent FDA expert panel focused largely on the risks of SSRIs during pregnancy; Dr. Freeman weighs in on the information provided in the report.
Essential Reads: Mirtazapine (Remeron) and Pregnancy
While we have adequate data to support the use of SSRI and SNRI antidepressants during pregnancy, there is less data regarding other classes of antidepressants. Although we less commonly use mirtazapine in pregnancy, several [...]
New Study Investigates the Impact of Prenatal SSRI Exposure on Brain Structure in Older Children
Maternal SSRI use during pregnancy may be associated with altered brain development in children; however, this study cannot fully rule out contributions of confounding genetic and enviromental factors.
What Has a Greater Effect on Children’s Behavior: Prenatal Exposure to Antidepressants or Maternal Depression?
Maternal depression during the third trimester, not prenatal SSRI exposure, was associated with higher levels of internalizing and anxiety behaviors in children from 3 to 12 years of age.
Essential Reads: Why Non-Randomized Studies Fall Short When Assessing Reproductive Safety
All of our information on the reproductive safety of medications comes from non-randomized studies. However, many of these studies fail to take into consideration other factors associated with maternal psychiatric illness which may also affect outcomes.
Largest Study Ever Shows No Increase in Risk of Neurodevelopmental Disorders in Kids Exposed to Antidepressants In Utero
Analyzing data from nearly 150,000 children with prenatal antidepressant exposure in two healthcare databases, a recent study finds no association between prenatal exposure to antidepressants and risk for neurodevelopmental disorders.
Essential Reads: What is the Best Screening Tool for Depression During Pregnancy?
Many women experience depression during pregnancy. What is the best way to identify these women?
Knowns and Unknowns About SSRI Use During Pregnancy in 2022
Dr. Lee S. Cohen, Director of the Ammon-Pinizzotto Center for Women's Mental Health at Massachusetts General Hospital, recently shared his insights on clinical issues regarding prescribing antidepressants during pregnancy with Ob.Gyn News on March 23, [...]
Language and Mathematical Skills in Danish Children with Prenatal Exposure to Antidepressants
Some studies have demonstrated associations between in utero exposure to antidepressants and cognitive outcomes.