A New Threat to Pregnancy: Xylazine
Xylazine, a veterinary sedative, has become an increasingly common adulterant in the illicit opioid supply, posing unique risks to pregnant individuals and their developing fetuses.
Xylazine, a veterinary sedative, has become an increasingly common adulterant in the illicit opioid supply, posing unique risks to pregnant individuals and their developing fetuses.
Prenatal cannabis exposure was associated with deficits in executive function and aggressive behavior; however, there are other important exposures to consider in this study.
In this study with over 4000 infants exposed to gabapentin, the information is reassuring. While we cannot rule out the possibility of a small increase in risk of cardiovascular malformations in gabapentin-exposed infants, gabapentin does not appear to be a major teratogen.Â
The psychostimulant lisdexamfetamine was well-tolerated and improved both subjective and objective measures of attention and working memory in women undergoing surgical menopause.
With ketamine and esketamine increasingly used to treat depression, especially in women of reproductive age, this study reveals important gaps in care, including inconsistencies in pregnancy testing, informed consent, and contraception practices among ketamine clinics in the United States.Â
Every week we review the most recent publications in women’s mental health.
In this large observational study, similar and, in some instances, more favorable neonatal and maternal outcomes were observed in pregnancies exposed to buprenorphine combined with naloxone compared to pregnancies exposed to buprenorphine alone.
This study provides valuable insight into the inequities in perinatal mental healthcare and suggests that the most significant barriers to mental healthcare may occur at the provider referral level.
Clinically significant anxiety symptoms are common during the postpartum period and frequently complicate the treatment of postpartum depression.  While SSRIs are indicted for the treatment anxiety symptoms, especially when they co-occur with depression, many women may need to use a benzodiazepine for managing more severe symptoms of anxiety or insomnia.Â
A study using indirect comparisons suggests that zuranolone is more effective than the SSRIs for the treatment of PPD. Should it be the first choice for treatment?