Pregnancy & Medications

New Research from the CWMH: Lithium During Pregnancy and Risk of Cardiovascular Malformations

  While we use lithium less commonly now than we have in the past, lithium is still one of the very best mood stabilizers we have.  And with regard to its reproductive safety, we have [...]

By |2025-06-26T09:07:52-04:00June 19th, 2017|Mood Stabilizers, Outcomes, Pregnancy & Medications, Research at CWMH, Risk of Malformations|Comments Off on New Research from the CWMH: Lithium During Pregnancy and Risk of Cardiovascular Malformations

Oxcarbazepine (Trileptal) and Pregnancy: Do We Have Enough Information?

  Last week in clinical rounds we discussed a case of a woman with bipolar disorder who was planning a pregnancy.  She had a long history of illness, experiencing primarily depressive episodes since her early [...]

By |2025-06-26T09:07:54-04:00June 7th, 2017|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Oxcarbazepine (Trileptal) and Pregnancy: Do We Have Enough Information?

Why Are We Still Using Valproic Acid (Depakote) in Women of Childbearing Age?

  There have long been concerns regarding the use of the anticonvulsant valproate (Depakote) during pregnancy.  First trimester use of valproate has been associated with a 3-5% risk of neural tube defects, as well as [...]

By |2020-11-26T08:28:56-04:00May 22nd, 2017|Anti-Epileptic Drugs, Pregnancy & Medications, Risk of Malformations|Comments Off on Why Are We Still Using Valproic Acid (Depakote) in Women of Childbearing Age?

Lamotrigine and Pregnancy: Meta-Analysis Shows No Increase in Risk for Malformations

  Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly used in this setting, including lithium and [...]

By |2025-06-26T09:07:02-04:00May 8th, 2017|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Lamotrigine and Pregnancy: Meta-Analysis Shows No Increase in Risk for Malformations

In Brief: Beta Blockers and Pregnancy, No Observed Increase in Risk of Malformations

Beta blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women.  They are also effective for the treatment of anxiety symptoms, most commonly performance anxiety. According to a report [...]

By |2017-05-04T15:29:30-04:00May 4th, 2017|Anti-Anxiety Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on In Brief: Beta Blockers and Pregnancy, No Observed Increase in Risk of Malformations

More Data on Pregabalin (Lyrica) and Pregnancy

Pregabalin (marketed in the US as Lyrica) is approved by the US Food and Drug Administration for the treatment of epilepsy, fibromyalgia, and neuropathic pain.  It is also used off-label to treat psychiatric disorders, most [...]

By |2017-05-02T15:49:43-04:00May 2nd, 2017|Anti-Anxiety Medications, Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on More Data on Pregabalin (Lyrica) and Pregnancy

Stimulants In Pregnancy and Increased Risk of Gestational Hypertension

  Our group has noted that we are seeing an increase in the number of consultations for women treated with psychostimulants in combination with an antidepressant.  The reasons vary.  Some women have depression and comorbid [...]

By |2020-11-26T08:30:35-04:00March 20th, 2017|Pregnancy & Medications|Comments Off on Stimulants In Pregnancy and Increased Risk of Gestational Hypertension

Synthetic Oxytocin and Its Effect on Postpartum Mood and Anxiety

Often referred to as the “hormone of love," oxytocin plays an important role in childbirth, maternal behavior, lactation, social affiliation, and sexual pleasure.  Levels of oxytocin, a neuropeptide produced by the hypothalamus and released into [...]

By |2017-03-15T10:50:21-04:00March 15th, 2017|Anxiety Disorders, Postpartum Psychiatric Disorders, Pregnancy & Medications|Comments Off on Synthetic Oxytocin and Its Effect on Postpartum Mood and Anxiety
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