Sage Therapeutics and Biogen Announce Plans to Submit a New Drug Application for Zuranolone to the FDA in 2022
The FDA will review zuranolone for the treatment of depression in the first half of 2022.
Essential Reads: A Comprehensive Review of Brexanolone for the Treatment of Postpartum Depression
This review discusses the novel neurosteroid antidepressant brexanolone for the treatment of postpartum depression.
Essential Reads: Zuranolone for Postpartum Depression
Zuranolone has antidepressant effects in women with severe PPD, observed as early as 3 days after initiation of treatment. Â
In Brief: Postpartum Depression Common in COVID-Positive Women Separated from Their Newborns
Women may experience depression and post-traumatic symptoms, especially those who were separated from their newborns after delivery and those with severe COVID-19 illness during pregnancy or after delivery.Â
Essential Reads: Strategies for the Prevention of Postpartum Depression
Postpartum depression (PPD) is a relatively common problem, affecting between 10% and 15% of women after delivery. Although it is difficult to reliably predict which women in the general population will experience postpartum depression, it [...]
Essential Reads: Evidence-Based Interventions for Depressed Mothers and Their Young Children
In a given year, about 10% of mothers in the United States experience a major depressive episode (MDE). Roughly translated, this means about 1 in 10 children is exposed to maternal depression each year (Ertel [...]
Recruiting New Mothers with Postpartum Depression for the Skylark Study
In 2019, brexanolone was introduced by Sage Therapeutics as Zulresso, a novel treatment for postpartum depression. The oral version of this novel antidepressant – SAGE 217 or zuranolone – is now finishing up its Phase [...]
Postpartum Depression: Unipolar or Bipolar?
About 15% of women will experience postpartum depression after the birth of a child. While most of those women will have unipolar depression, a certain number of women will have bipolar depression. At this juncture, [...]
Childbirth-Related PTSD and Postpartum Depression Commonly Occur Together
Post-traumatic stress disorder (PTSD) is common among women of child-bearing age. While we are increasingly attentive to screening for depressive symptoms during pregnancy and after delivery, less often do we inquire about PTSD symptoms. [...]
Mindfulness Training During Pregnancy Reduces Risk of Postpartum Depression
The US Preventive Services Task Force (USPSTF) issued recommendations that all pregnant and postpartum women should be evaluated in order to determine risk for depressive illness and recommends that women at increased risk for [...]