Outcomes - MGH Center for Women's Mental Health

Pregnancy and SSRIs: Is There a Risk to the Newborn?

The increasing number of reproductive-age women taking antidepressants has raised concerns about the potential risks of using these medications during pregnancy. Literature accumulated over the last decade supports the use of certain selective serotonin reuptake inhibitors (SSRIs) and the older tricyclic antidepressants during pregnancy, indicating no increased risk of congenital malformation in children exposed to these medications during the first trimester of pregnancy. Still, questions remain regarding the purported risk for “toxicity” in newborns exposed to antidepressants around the time of labor and delivery. These concerns are not new. Twenty years ago, case reports suggested that maternal use of tricyclic antidepressants near the time of delivery was associated with problems in the newborn such as difficulty feeding, restlessness, or jitteriness.

By MGH Center for Women's Mental Health|2015-07-21T11:39:06-04:00October 15th, 2004|Antidepressants, Neonatal Symptoms, Outcomes, Pregnancy & Medications|Comments Off

Reevaluating the Pros and Cons of Hormone Replacement Therapy

Each year, more than 1.3 million American women become menopausal in the U.S. The menopausal transition is marked by intense hormonal variability, and frequently accompanied by vasomotor symptoms (e.g., hot flashes, night sweats), sleep disturbance, and altered libido. In addition, as women become estrogen-deprived, they may also experience an increased risk for osteoporosis, cardiovascular disease, cognitive dysfunction, and depressive symptoms.

By MGH Center for Women's Mental Health|2015-07-20T11:48:35-04:00September 18th, 2002|Hormone Therapy, Menopausal Symptoms, Outcomes|Comments Off

Breastfeeding Boosts Intelligence

Over the years, various studies have demonstrated the many advantages of breastfeeding, findings that have led the American Academy of Pediatrics to recommend that all mothers breastfeed their children for the first year of the child's life. Several studies have also examined the relationship between breastfeeding and intellectual development in younger children and have demonstrated better cognitive functioning in children who were breastfed. The extent to which breastfeeding during infancy has an effect on later intellectual development has been more difficult to assess.

By MGH Center for Women's Mental Health|2015-07-20T11:05:48-04:00July 18th, 2002|Breastfeeding & Medications, Outcomes, Postpartum Psychiatric Disorders|Comments Off

Depression and Preterm Labor

Although most people tend to think of pregnancy as a time of emotional well-being, depression is relatively common, affecting about 1 in 10 women. While there are obvious concerns related to the use of antidepressants during pregnancy and the effects of these medications on the developing fetus, less attention has focused on the impact of depression itself on the pregnancy. A recent study suggests that women with depression may be at greater risk for preterm labor.

By MGH Center for Women's Mental Health|2015-07-20T10:48:28-04:00April 30th, 2002|Depressive Disorders, Outcomes, Pregnancy Outcomes, Psychiatric Disorders During Pregnancy|Comments Off

Lithium Discontinuation While Attempting to Conceive

For women with bipolar disorder who are planning a pregnancy, it is common practice to discontinue mood stabilizers prior to attempts to conceive, since the mood stabilizers most commonly used to treat bipolar disorder (lithium, valproic acid, and carbamazepine) all carry some risk of birth defect. The problem with this approach is that, after discontinuation of maintenance treatment, a woman is at very high risk for relapse. The longer it takes to get pregnant and the longer she remains off medication, the greater is her risk for having recurrent illness.

By Ruta Nonacs, MD PhD|2024-04-14T16:20:24-04:00February 6th, 2002|Bipolar Disorder, Mood Stabilizers, Outcomes, Psychiatric Disorders During Pregnancy|Comments Off