Neurodevelopmental Disorders

Essential Reads: The Impact of Prenatal Lithium Exposure on Offspring Cognitive Functioning

This clinical cohort study showed no impact of prenatal lithium exposure on cognitive functioning in children 6 to 14 years of age.

By |2021-10-20T10:21:06-04:00October 20th, 2021|Essential Reads, Mood Stabilizers, Neurodevelopmental Disorders, Pregnancy & Medications|Comments Off on Essential Reads: The Impact of Prenatal Lithium Exposure on Offspring Cognitive Functioning

Essential Reads: Neurodevelopmental Outcomes in Children with Prenatal Exposure to Antiepileptic Drugs

There is a growing body of literature to indicate that exposure to certain antiepileptic drugs, most notably valproic acid (VPA, Depakote) during critical periods of development may be associated with long-lasting neurodevelopmental deficits.

By |2025-06-26T09:07:34-04:00September 1st, 2021|Anti-Epileptic Drugs, Essential Reads, Neurodevelopmental Disorders, Pregnancy & Medications|Comments Off on Essential Reads: Neurodevelopmental Outcomes in Children with Prenatal Exposure to Antiepileptic Drugs

Essential Reads: Emerging Evidence of the Long-Term Effects of Cannabis on the Developing Brain

Despite decreasing rates of alcohol and tobacco use during pregnancy, the use of cannabis use during pregnancy is on the rise.  We are seeing an increasing number of women in our clinic who are using [...]

By |2021-11-04T08:32:17-04:00February 10th, 2021|Cannabis, Essential Reads, Neurodevelopmental Disorders, Outcomes, Perinatal Substance Use|Comments Off on Essential Reads: Emerging Evidence of the Long-Term Effects of Cannabis on the Developing Brain

Prenatal Exposure to Valproic Acid Linked to Increased Risk for Autism, ADHD

Prenatal exposure to valproate has been associated with an elevated risk (10%) for a broad range of congenital malformations including neural tube defects, as well as adverse neurodevelopmental sequelae, including lower IQ and developmental delays [...]

By |2025-06-26T09:07:37-04:00February 9th, 2021|Anti-Epileptic Drugs, Neurodevelopmental Disorders, Outcomes, Pregnancy & Medications|Comments Off on Prenatal Exposure to Valproic Acid Linked to Increased Risk for Autism, ADHD

Prenatal Valproic Acid (Depakote) Exposure Increases Risk for Neurodevelopmental Disorders

While we have considerable information regarding the teratogenic risk associated with prenatal exposure to various antiepileptic drugs (AEDs), we have considerably less information on the impact of exposure to AEDs on behavioral outcomes in [...]

By |2025-06-26T09:07:38-04:00November 11th, 2020|Anti-Epileptic Drugs, Neurodevelopmental Disorders, Outcomes, Pregnancy & Medications|Comments Off on Prenatal Valproic Acid (Depakote) Exposure Increases Risk for Neurodevelopmental Disorders

Opioid Exposure During Pregnancy, Long-Term Effects on Children’s Development

According to a recent analysis of national data by the Centers for Disease Control, the number of pregnant women with opioid use disorder (as documented at the time of delivery) more than quadrupled from 1999 [...]

By |2019-07-10T13:38:26-04:00July 22nd, 2019|Neurodevelopmental Disorders, Opioids, Outcomes, Perinatal Substance Use|Comments Off on Opioid Exposure During Pregnancy, Long-Term Effects on Children’s Development

Behavior Problems More Common In Children with Prenatal Exposure to Valproic Acid

While we have considerable information regarding the teratogenic risk associated with prenatal exposure to various antiepileptic (AED) drugs, we have less impact on exposure to AEDs on behavior outcomes in children.  Several studies have shown [...]

By |2025-06-26T09:07:41-04:00July 15th, 2019|Anti-Epileptic Drugs, Neurodevelopmental Disorders, Outcomes, Pregnancy & Medications|Comments Off on Behavior Problems More Common In Children with Prenatal Exposure to Valproic Acid

Smoking During Pregnancy and Risk for ADHD in Children

Previous studies have demonstrated that children born to mothers who smoke during pregnancy are at increased risk for attention-deficit/hyperactivity disorder (ADHD).  In a recent review, Huang and colleagues looked at data from 15 cohort studies [...]

By |2019-06-18T17:52:36-04:00June 19th, 2019|Neurodevelopmental Disorders, Nicotine, Outcomes, Perinatal Substance Use|Comments Off on Smoking During Pregnancy and Risk for ADHD in Children

Prenatal Exposure to Valproic Acid: ADHD and Other Deficits in Cognitive Functioning

Previous studies have shown that children exposed to antiepileptic drugs (AEDs) during pregnancy may be at increased risk for neurodevelopmental disorders.  In a recent population-based cohort study from Denmark, researchers examined the prevalence of [...]

By |2025-06-26T09:07:45-04:00January 11th, 2019|Anti-Epileptic Drugs, Neurodevelopmental Disorders, Pregnancy & Medications|Comments Off on Prenatal Exposure to Valproic Acid: ADHD and Other Deficits in Cognitive Functioning

Parental Age and Risk of ADHD in Children

Many studies have examined the association between parental age and psychiatric illness in the children, including autism and schizophrenia.  In a recent case-control study from Finland, the authors identified 10,409 individuals with ADHD born between 1991 and 2005 from nationwide population-based registers.  Logistic regression was used to examine the association between parental age and ADHD in the offspring, adjusting for potential confounding factors including parental psychiatric history, maternal socioeconomic status, marital status, maternal smoking during pregnancy, number of previous births, and birth weight.

By |2015-07-08T14:07:59-04:00April 7th, 2015|Neurodevelopmental Disorders, Outcomes, Psychiatric Disorders During Pregnancy|Comments Off on Parental Age and Risk of ADHD in Children
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