Antidepressants

Assessing the Reproductive Safety of Antidepressants: Can Non-Randomized Studies Provide the Information We Need?

Perinatal psychiatry is a field in which we treat vulnerable patients, a mother and her child, where both the illness we are treating and the treatments we prescribe have the potential to affect the outcome.  [...]

By |2020-09-09T17:43:09-04:00September 3rd, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Assessing the Reproductive Safety of Antidepressants: Can Non-Randomized Studies Provide the Information We Need?

Another Study on Antidepressants and Birth Defects: Does it Change Our Decision-Making?

Prozac (fluoxetine) was the first SSRI or selective serotonin reuptake inhibitor.  Since its release in 1988, we have been gathering data on the reproductive safety of fluoxetine and other SSRIs.  Over the last 32 years, [...]

By |2020-11-26T08:23:09-04:00August 25th, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Another Study on Antidepressants and Birth Defects: Does it Change Our Decision-Making?

What is the Risk for Relapse After Stopping Antidepressants During Pregnancy?

For women taking antidepressants, how do we decide whether or not they should maintain their medication during pregnancy? Based on our previous research and clinical experiences, we know that many women who discontinue antidepressant [...]

By |2020-07-07T11:08:49-04:00July 1st, 2020|Antidepressants, Psychiatric Disorders During Pregnancy|Comments Off on What is the Risk for Relapse After Stopping Antidepressants During Pregnancy?

Clinical Update 2020: New Data on Duloxetine and Pregnancy

A few weeks ago, we published a clinical update for duloxetine (Cymbalta) and pregnancy, stating that there was little new to report since we last covered the topic in 2015.  It is somewhat amusing [...]

By |2020-08-13T14:28:20-04:00March 6th, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2020: New Data on Duloxetine and Pregnancy

Clinical Update 2020: Duloxetine and Pregnancy

Women face difficult choices when deciding whether or not to continue psychiatric medications during pregnancy.  For many years, we have typically recommended the older antidepressants, including the selective serotonin reuptake inhibitors or SSRIs such [...]

By |2020-08-10T12:44:33-04:00February 25th, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2020: Duloxetine and Pregnancy

Clinical Update 2019: Tamoxifen and Antidepressants

Women receiving tamoxifen for the treatment or prevention of breast cancer should be aware of possible drug-drug interactions between tamoxifen and specific antidepressant medications.  Antidepressants are used widely to treat depression and anxiety disorders in [...]

By |2020-02-13T21:33:15-04:00November 5th, 2019|Antidepressants, Breast Cancer, Menopausal Symptoms|Comments Off on Clinical Update 2019: Tamoxifen and Antidepressants

Fluvoxamine and Pregnancy: Is There a Right Choice?

  Every day, we see women in our clinic who are deciding whether to continue a selective serotonin reuptake inhibitor (SSRI) for management of depression or anxiety during pregnancy. As a class, SSRI use during [...]

By |2018-09-10T12:34:17-04:00May 16th, 2018|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Fluvoxamine and Pregnancy: Is There a Right Choice?

Why Do Many Continue To Recommend Tapering SSRI Antidepressants During the Third Trimester?

  In 2005, we saw the first reports describing an increased risk of “poor neonatal adaptation” in infants with prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants in late pregnancy.  Since that time, studies [...]

By |2020-11-26T08:26:29-04:00September 19th, 2017|Antidepressants, Pregnancy & Medications|Comments Off on Why Do Many Continue To Recommend Tapering SSRI Antidepressants During the Third Trimester?

No Association Between Intellectual Disability and Prenatal Antidepressant Exposure

We have long been interested in understanding the effects of prenatal exposure to antidepressants on the development of the fetal brain.  The earliest studies addressing this question were small but yielded detailed (and reassuring) information [...]

By |2017-07-25T09:16:39-04:00July 25th, 2017|Antidepressants, Pregnancy & Medications|Comments Off on No Association Between Intellectual Disability and Prenatal Antidepressant Exposure
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