Dehydroepiandrosterone (DHEA) Â is a steroid hormone produced by humans. Â It functions as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids. Â Â In a recent study, presented at the annual meeting [...]
The first two articles look at the risk of autism spectrum disorders (ASD) in children exposed to SSRIs during pregnancy. Â We will review these studies in greater detail next week. They both indicate that [...]
While we have considerable data on the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, most of this research focuses on the risk of congenital malformations in exposed children. Â We have far less [...]
In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD). Â SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of [...]
Happy New Year! Only a week into 2019, there is no shortage of articles to review and discuss. Â Over the last week, the article that has received the most press is the one documenting [...]
Another year, and an opportunity to reflect on the past year.  It has been another very active year in the field of women’s mental health, with no shortage of articles in this field.  We continue [...]
Pregnancy-associated mortality, defined as the death of a woman during pregnancy or within one year of the termination of pregnancy, is increasing in Massachusetts. Â In 2012, there were 30.4 deaths/100,000 live births. In 2014, the [...]
While we have identified various sociodemographic variables as factors which modulate vulnerability to menopausal symptoms, no studies (to my knowledge) have looked at how a history of intimate partner violence (IPV) or other traumatic exposures [...]
What’s worse? Prenatal exposure to antidepressant medications or exposure to maternal depression?  Hutchison and colleagues observe that worse executive functioning was observed in the 6-year-old children of mothers with higher levels of depressive symptoms.  Prenatal [...]
Earlier this year the American College of Obstetricians and Gynecologists (ACOG) released a revised Committee Opinion calling for a new paradigm for postpartum care in the United States. Â Moving away from the single postpartum check [...]
