Weekly Roundup for June 16, 2017: Recent Publications in Women’s Mental Health
This roundup has some really interesting and clinically relevant articles. The first one, from Palomo and colleagues, evaluates risk for cardiovascular malformations in children prenatally exposed to lithium. Yang and colleagues look at neonatal discontinuation symptoms in children exposed to SNRIs and SSRIs and conclude that they are more related to prematurity than to exposure to antidepressants. Analyzing data from Danish Medical Register, researchers note that first onset of depression or [...]
New Study Questions Prolonged Room-Sharing for Infants
In 2016, the American Academy of Pediatrics (AAP) issued new infant sleep guidelines, recommending that infants should sleep in the same room as their parents – on a separate firm sleep surface, such as a crib or bassinet -- to decrease the risk of SIDS and other sleep-related deaths. The following 19 recommendations are based on epidemiologic studies which have identified risk factors for sleep-related deaths during the first year of [...]
Does Baby-Friendly Have to Be Mom-Unfriendly?
We’ve all heard it: Breast is Best. We all know what it means. And if you have had a baby at some point over the last ten years, you have been encouraged, and maybe even pressured, to breastfeed your baby. Breastfeeding has become the foundation of what it means to be a good mother, and when new mothers do not or are not able to exclusively breastfeed their baby, they often [...]
Oxcarbazepine (Trileptal) and Pregnancy: Do We Have Enough Information?
Last week in clinical rounds we discussed a case of a woman with bipolar disorder who was planning a pregnancy. She had a long history of illness, experiencing primarily depressive episodes since her early 20’s. The only mood stabilizer that seems to have worked for her has been oxcarbazepine (Trileptal) and she is currently taking 300 mg twice per day. Previous medication trials included lithium, lamotrigine, and carbamazepine. None of [...]
Weekly Roundup for June 2, 2017: Recent Publications in Women’s Mental Health
Sometimes a weekly roundup turns into a monthly roundup. Sorry about that. From the PACT Consortium, we have a study defining distinct subtypes of perinatal depression which differ in terms of severity and timing of onset. Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium. Putnam KT, Wilcox M, Robertson-Blackmore E, Sharkey K, Bergink V, Munk-Olsen T, Deligiannidis KM, Payne J, Altemus M, [...]
Lamotrigine Reduces Risk for Postpartum Relapse in Women with Bipolar Disorder
Numerous studies have demonstrated that women with histories of bipolar disorder are at high risk for postpartum illness. Because of this increased risk for relapse during the postpartum period, we typically recommend that women with histories of bipolar disorder continue treatment with a mood stabilizer throughout the postpartum period. Historically, lithium has been the most commonly used mood stabilizer, and there is solid data to indicate that lithium initiated during pregnancy [...]