In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression (PPD). SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors. This drug was initially [...]
The American College of Obstetricians and Gynecologists (ACOG) has made a significant change to its recommendations for optimal postpartum care. Previously, ACOG has recommended that women receive a single, comprehensive postpartum visit within the first [...]
Over the last few weeks, there has been a lot of coverage of a story involving a new mother from Sacramento. You can read the details of the story here and here. Basically, a new [...]
Over the last decade, there has been increased interest around the country in establishing consistent screening for perinatal depression across a range of clinical settings. Approximately 40 states have instituted guidelines and recommendations regarding screening [...]
While many women are at risk for postpartum depression, we continue to struggle in providing adequate support and care to women in this setting, especially socioeconomically disadvantaged women. In a randomized clinical trial including [...]
In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression. SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors. This drug was initially under [...]
Because estrogen-containing contraceptives may affect lactation and may increase the risk of thrombosis, progestin-only contraceptives are used in women who are breastfeeding. Depo-Provera (DMPA), which contains medroxyprogesterone, is frequently used during the immediate postpartum period [...]
As we move toward universal screening for perinatal depression, one of our most significant challenges will be to evaluate and deliver care to the women who are identified as being depressed. It is discouraging [...]
Biomarkers (or biological markers) are used in many fields of medicine to provide objective information on normal or pathological biological processes and to predict response to therapeutic interventions. Researchers have long searched for biomarkers which [...]
Women are at significant risk for severe psychiatric illness after childbirth, particularly during the first three months. Suicide is a rare but tragic outcome of untreated psychiatric illness in this setting. In order to prevent [...]
