• perinatal depression

    History of Stillbirth Increases Risk for Depression, Anxiety During Subsequent Pregnancies

    Perinatal loss is a traumatic event for women and their families.  While we clearly understand the potential for perinatal loss to cause significant emotional consequences, we have relatively little data on the prevalence of anxiety [...]

    Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

    In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]

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