• hot flashes

    Pregabalin (Lyrica) for the Treatment of Hot Flashes

    Although estrogen is highly effective for the treatment of hot flushes, many women are reluctant to use hormone therapy to manage these symptoms, given recent concerns that estrogen may carry certain risks.  Several studies have demonstrated that gabapentin (Neurontin) and certain antidepressants, including paroxetine (Paxil) and venlafaxine (Effexor), may be useful non-hormonal treatments for the management of hot flashes.  Data presented at the annual meeting of the American Society of Clinical Oncology indicate that pregabalin (Lyrica), an anticonvulsant drug similar to gabapentin, may also be helpful for alleviating hot flashes.

    By |2015-08-12T15:19:18-04:00September 21st, 2009|Menopausal Symptoms|4 Comments

    Hot Flashes or Depression: Which Comes First?

    Hot flashes and depression are both common symptoms of the menopause transition.  Several studies have found a relationship between depression and hot flashes: depressed women are more likely to experience hot flashes and women with hot flashes are more likely to have depression.  Other studies have found no association between hot flashes and depression. 

    By |2015-08-12T15:09:09-04:00September 14th, 2009|Menopausal Symptoms|0 Comments

    Use of Complementary and Alternative Medicines for Menopausal Hot Flashes

    Approximately seventy percent of all women experience hot flashes and/or night sweats (also called vasomotor symptoms) during the menopause transition (Stearns et al. 2002).  Until recently, estrogen therapy was the treatment of choice for most women who sought treatment for hot flashes.  Since the results of the Women's Health Initiative in 2002 noted risks of prolonged use of hormone therapy in older postmenopausal women (Roussouw et al. 2002), many women pursue other treatments for their hot flashes, including over-the-counter complementary and alternative medicines (CAMs), including soy isoflavones, black cohosh, and omega-3 fatty acids.  However, there is limited evidence to support the use of these treatments for hot flashes to date.

    Phytoestrogens and Menopause

    For decades, estrogen was used as a component of hormone replacement therapy to treat menopausal symptoms and for anticipated preventative health benefits in women with prostesterone, or as a monotherapy hormone treatment in women after hysterectomy, but after studies reported that long-term estrogen increase the prevalence of cardiovascular events and breast cancer, many patients and researchers have looked into alternative treatments such as food or products containing phytoestrogens.  Phytoestrogens are weak plant-derived estrogens that are structurally similar to estrogen hormones produced by the body.

    Acupuncture for Hot Flushes in Women with Breast Cancer

    Many women report vasomotor symptoms, including hot flushes and night sweats, during the menopausal transition. While estrogen is clearly one of the most effective treatments for vasomotor symptoms, recent concerns regarding the use of hormone replacement therapy (HRT) have made treaters much more reluctant to recommend HRT, even for short-term management of vasomotor symptoms.

    By |2015-08-11T15:17:58-04:00September 30th, 2008|Menopausal Symptoms|0 Comments

    Cognitive-Behavioral Therapy for the Treatment of Menopausal Hot Flashes: A Pilot Study

    Hot flashes are a common and distressing symptom of menopause, affecting approximately 60-70 % of women undergoing the menopausal transition. Several pharmacologic treatments for hot flashes, including hormone replacement therapy (HRT) and some antidepressants, have been shown to reduce the frequency and intensity of hot flashes. However, some women prefer not to use HRT or antidepressants and seek alternative treatments, such as homeopathic or herbal remedies. Many of these alternative treatments have not yet been evaluated for safety or efficacy.

    By |2015-08-11T15:16:17-04:00September 29th, 2008|Menopausal Symptoms|0 Comments

    Citalopram (Celexa) Effective for Treating Hot Flashes

    For decades, estrogen has been used to treat menopausal symptoms, including night sweats and hot flushes.  However, after studies reported that estrogen may have an adverse effect on risk for cardiovascular disease and breast cancer, many patients and clinicians have looked into alternative treatments for hot flashes, including selective serotonin reuptake inhibitors (SSRIs).

    Acupuncture for the Treatment of Menopausal Hot Flashes

    Many women report vasomotor symptoms, including hot flushes and night sweats, during the menopausal transition. While estrogen is clearly one of the most effective treatments for vasomotor symptoms, recent concerns regarding the use of hormone replacement therapy (HRT) have made treaters much more reluctant to recommend HRT, even for short-term management of vasomotor symptoms. A recent study has demonstrated that acupuncture may be an effective non-hormonal treatment for vasomotor symptoms.

    Escitalopram for Menopause-Related Depression and Vasomotor Symptoms

    Every year more than 1.7 million women in the United States enter into menopause. During this time of hormonal fluctuations it is typical for women to experience hot flashes, night sweats and sleep disturbance. More recently, studies have identified an association between menopausal transition and an increased risk for developing depressive symptoms (Harlow et al., 2003; Freeman et al., 2004). It is not clear how physicians and patients should deal with menopause-related physical and emotional symptoms. While hormone therapy effectively treats insomnia and hot flashes, the results have been mixed in treating mood and anxiety symptoms. Moreover, the safety of long-term use of hormone therapy is not known.

    By |2015-07-23T14:19:33-04:00December 30th, 2005|Menopausal Symptoms|1 Comment

    Venlafaxine (Effexor) for Postmenopausal Hot Flushes

    During the menopausal transition, up to 85% of women experience vasomotor symptoms of hot flushes and night sweats. For many women, hot flushes may be severe; they can interfere with work and other daily activities and affect sleep quality. Hot flushes may be associated with fatigue, poor concentration, and depression. Given the recent data from the Women's Health Initiative regarding the risks associated with long-term use of estrogen, many peri- and post-menopausal women are understandably reluctant to take menopausal hormone therapy for the treatment of hot flushes, despite its proven efficacy. Given these concerns, there is a clear need for alternative non-hormonal therapies for the treatment of hot flushes and other menopause-related symptoms.

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