Depo-Provera

Depression and Hormonal Contraception: Should Depo-Provera Be Used in Postpartum Women?

Because estrogen-containing contraceptives may affect lactation and may increase the risk of thrombosis, progestin-only contraceptives are used in women who are breastfeeding.  Depo-Provera (DMPA), which contains medroxyprogesterone, is frequently used during the immediate postpartum period [...]

You Asked: Do Progestin-Only Contraceptives Cause Postpartum Depression?

One of our readers contacted us noting that she developed a severe episode of postpartum depression after receiving an injection of the contraceptive, Depo-Provera.  She is pregnant again and now wonders if she should avoid [...]

Does Depo-Provera Cause Mood Changes?

Depo-Provera (DMPA), also known as the birth control shot, is a highly effective form of contraception that lasts for 3 months, and thus requires only 4 injections per year. DMPA contains a long-lasting form of depot medroxyprogesterone acetate that works as a contraceptive agent by preventing the ovaries from releasing an egg each month. Potential side effects of DMPA include bone density loss, weight gain, and mood worsening. Although depression is listed in the packet insert as a side effect of the injection, available research addressing this side effect are limited and contradictory.