Postpartum psychosis (PPP) is a serious condition, occurring in 1 to 2 per 1000 women in the weeks after delivery and associated with extreme delirium-like behavior, delusions, hallucinations, and an increased risk of suicide and [...]
In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression (PPD). SAGE-547, now called brexanolone, is an allosteric modulator of GABA-A receptors. We saw the preliminary [...]
In the United States, about one out of every 160 pregnancies ends in stillbirth, defined as a pregnancy loss occurring after 20 weeks' gestation. Perinatal loss is a traumatic event for women and their families. [...]
In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression (PPD). SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors. This drug was initially [...]
A history of maternal psychiatric illness has been linked to postpartum depression (PPD), but this does not account for all instances of postpartum psychiatric illness. A recent study examined the impact of medical complications during [...]
The American College of Obstetricians and Gynecologists (ACOG) has made a significant change to its recommendations for optimal postpartum care. Previously, ACOG has recommended that women receive a single, comprehensive postpartum visit within the first [...]
Even as perinatal mood and anxiety disorders have garnered more attention over the past several years, the most feared consequence of these disorders, suicide, remains a phenomenon that requires greater understanding. While suicide is a [...]
Over the last decade we have seen multiple studies which have demonstrated an association between the use of antidepressants during pregnancy and increased risk of certain adverse outcomes, including preterm birth and low birth weight. [...]
The American Academy of Pediatrics (AAP) now recommends that babies sleep in the same room as their mothers. "SIDS and Other Sleep-Related Infant Deaths: Updated 2016 Recommendations for a Safe Infant Sleeping Environment," was [...]
Over the last few weeks, there has been a lot of coverage of a story involving a new mother from Sacramento. You can read the details of the story here and here. Basically, a new [...]
