MGH Center for Women's Mental Health

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So far MGH Center for Women's Mental Health has created 1457 blog entries.

Lithium: Women More Vulnerable to Adverse Effects Than Men

Lithium is one of the most effective treatments for patients with bipolar disorder.  Its use, however, is limited by its potential for serious long-term adverse events, including renal, thyroid, and parathyroid dysfunction. A recent study [...]

By |2016-07-20T10:18:02-04:00July 14th, 2015|General, Mood Stabilizers, Treatment|Comments Off on Lithium: Women More Vulnerable to Adverse Effects Than Men

NAMS Position Statement on the Use of Hormone Therapy in Women Over 65

Since the Women's Health Initiative (WHI) reported that the risks of menopausal hormone replacement therapy (HRT) outweighed its benefits, there has been a significant reduction in the use of HRT.  However, since that time, studies [...]

By |2015-07-14T17:40:35-04:00July 13th, 2015|Hormone Therapy, Menopausal Symptoms, Treatment, Vasomotor Symptoms|Comments Off on NAMS Position Statement on the Use of Hormone Therapy in Women Over 65

Antidepressants and Pregnancy: Are Some SSRIs Safer Than Others?

  Over the last decade, numerous studies on the reproductive safety of selective serotonin reuptake inhibitors (SSRIs) have been published.  However, these studies, using different methodologies and studying different populations, have often yielded conflicting results. [...]

By |2020-11-26T08:39:16-04:00July 10th, 2015|Antidepressants, Outcomes, Pregnancy & Medications|Comments Off on Antidepressants and Pregnancy: Are Some SSRIs Safer Than Others?

SAGE-547: A Novel Treatment for Severe Postpartum Depression?

SAGE-547 (SAGE Therapeutics) is a new drug, an allosteric modulator of GABAA receptors, which is currently under investigation for the treatment of refractory seizure disorders.  It turns out that SAGE-547 may also be useful for [...]

By |2016-07-12T15:32:07-04:00July 7th, 2015|Medication, Postpartum Depression, Postpartum Psychiatric Disorders, Treatment|Comments Off on SAGE-547: A Novel Treatment for Severe Postpartum Depression?

New Research from the CWMH: Armodafinil for Menopause-Related Fatigue

Several recent articles indicate that the burden of menopausal symptoms is greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the [...]

By |2018-06-08T07:04:00-04:00July 6th, 2015|Menopausal Symptoms, Research at CWMH|Comments Off on New Research from the CWMH: Armodafinil for Menopause-Related Fatigue

New Research from the CWMH: Both Estradiol and Venlafaxine Improve Quality of Life in Perimenopausal Women with Hot Flashes

In healthy perimenopausal women with hot flashes, treatment with both estradiol and venlafaxine resulted in significantly greater improvement in quality of life, as compared to placebo. Estradiol had beneficial treatment effects on all domains of the [...]

By |2016-03-31T21:53:24-04:00June 30th, 2015|Menopausal Symptoms, Research at CWMH|Comments Off on New Research from the CWMH: Both Estradiol and Venlafaxine Improve Quality of Life in Perimenopausal Women with Hot Flashes

Depression in Fathers Affects Bonding

Multiple studies have shown that postpartum depression can interfere with bonding between the mother and her infant. While new fathers may also develop depression, little is known about how depression in the father affects bonding. [...]

By |2015-07-09T11:52:58-04:00June 30th, 2015|Child Outcomes, Outcomes, Postpartum Depression, Postpartum Psychiatric Disorders|Comments Off on Depression in Fathers Affects Bonding

Adjunctive Treatment with Medroxyprogesterone in Women with Acute Mania

Women with bipolar disorder often experience fluctuating mood symptoms across the menstrual cycle, typically reporting an exacerbation of symptoms during the premenstrual phase of the cycle (Rasgon et al, 2003, 2005).  Other studies have indicated [...]

By |2015-07-07T14:55:02-04:00June 24th, 2015|Bipolar Disorder, General, Hormone Therapy, Treatment|Comments Off on Adjunctive Treatment with Medroxyprogesterone in Women with Acute Mania

Brief Report: TMS for Depression During Pregnancy

Transcranial magnetic stimulation or TMS is similar to ECT but uses electromagnetic pulses to generate electrical current in specific regions of the brain that are known to modulate mood.  TMS is less likely to cause [...]

By |2016-07-20T10:26:15-04:00June 23rd, 2015|Depressive Disorders, Psychiatric Disorders During Pregnancy, Treatment|Comments Off on Brief Report: TMS for Depression During Pregnancy
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