This week’s offering includes an article published in Pediatrics indicating that cannabis metabolites are found in the breast milk up to 6 days after the last use. A small prospective study from Wisner and colleagues [...]
In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression (PPD). SAGE-547, now called brexanolone, is an allosteric modulator of GABA-A receptors. We saw the preliminary [...]
August 23, 2018 from ObGynNews The management of bipolar disorder during pregnancy is a critical clinical situation demanding great attention to issues such as reproductive safety of psychiatric medications used by women with bipolar disorder [...]
Data on the most recent randomized controlled trial of brexanolone, a novel treatment for postpartum depression, were released. (We will review those in greater detail next week.) Guidelines for the treatment of perimenopausal depression were [...]
Psychiatric Medications and Reproductive Safety: Scientific and Clinical Perspectives Pertaining to the US FDA Pregnancy and Lactation Labeling Rule. Freeman MP, Farchione T, Yao L, Sahin L, Taylor L, Huybrechts KF, Nonacs R, Sosinsky AZ, [...]
A recent article published in JAMA Internal Medicine raises concerns regarding the increasing use of marijuana in pregnant women. According to data derived from two small surveys, women reported using marijuana to alleviate morning sickness, [...]
This week, we have some data from our National Pregnancy Registry of Psychiatric Medications looking at infants exposed to quetiapine (Seroquel). Consistent with other studies we have seen recently, there appears to be no increase [...]
The newer “atypical” or second-generation antipsychotic agents are now used to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders. The National Pregnancy Registry for Atypical Antipsychotics [...]
Some interesting reviews on the list this week, including some excellent articles from leaders in the field which will be coming out in the September issue of Obstetrics & Gynecology Clinics of North America. [...]
Early observational studies suggested that hormone replacement therapy (HRT) may improve cognitive functioning in postmenopausal women; however, larger studies, including the Women’s Health Initiative, have shown that estrogen replacement therapy started in postmenopausal women (65 [...]
