At the top of the list is our most recent review on the reproductive safety of psychotropic medications. Â Molenaar and colleagues look at the incidence of perinatal depression in women with pregravid histories of major [...]
Peri- and post-menopausal women frequently complain of insomnia or poor sleep quality. Sleep disturbance is often attributed to nocturnal hot flashes; however, a study from researchers at Wayne State University School of Medicine suggests that [...]
While depression is a relatively common occurrence during the perinatal period, suicide is less common in pregnant and postpartum women than in other populations. Â Because suicide in this population is rare, we have limited information [...]
Most women with depression experience considerable difficulty in making decisions about whether or not to use antidepressant medications during pregnancy. These decisions are very complex, and women must consider their own illness history and personal [...]
Since the the Food and Drug Administration (FDA) approved brexanolone as an intravenous infusion for the treatment of postpartum depression last week, we have been deluged with questions from patents, providers and the media regarding [...]
The excitement over the FDA approval of brexanolone (to be marketed as Zulresso) is a good place to start this week’s roundup.  Brexanolone is a derivative of the neurosteroid allopregnanolone, and, while Zulpresso was approved [...]
Several weeks ago, the US Preventive Services Task Force (USPSTF) issued recommendations that all pregnant and postpartum women should be evaluated in order to determine risk for depressive illness and suggests that women at increased [...]
In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD). Â SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors. Â Since that time, Sage Therapeutics [...]
This week another study highlights the importance of prenatal vitamins in reducing the risk of autism spectrum disorders (ASD). Â This study from Schmidt and colleagues focused on high-risk families. In these families, one child had [...]
Postpartum depression (PPD) is a common and complicated illness, affecting about 15% of women in the perinatal period. Recent research from the PACT consortium (Postpartum Depression: Action Toward Causes and Treatment) has sought to classify [...]
