MGH Center for Women's Mental Health

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Risk of Depression is High in the Parents of Young Children

The New York Times published an interesting article on the high risk of depression among new parents.  While we are now more aware of depression in mothers after delivery and making greater efforts to screen for postpartum depression, the article points out that both parents are at risk for depression and that the risk extends well beyond the immediate postpartum period.

By |2018-07-11T13:25:05-04:00October 5th, 2010|Depressive Disorders, Postpartum Psychiatric Disorders, Prevalence & Risk Factors|Comments Off on Risk of Depression is High in the Parents of Young Children

Clinical Update 2010: Use of Stimulant Medications in Pregnancy

Approximately 4% of the adult population suffers from ADHD. Attention and executive functioning difficulties also occur in those with mood and psychotic disorders and require treatment strategies similar to those used to address ADHD symptoms. First line medications most often used to treat ADHD in adults are Dextroamphetamine (Dexedrine, Adderall) and Methylphenidate (Concerta, Ritalin, Metadate).

By |2017-12-22T13:05:25-04:00September 27th, 2010|ADHD Medications, Outcomes, Pregnancy & Medications|Comments Off on Clinical Update 2010: Use of Stimulant Medications in Pregnancy

Discontinuation of Antidepressants: Slower is Better

About half of all pregnancies are unplanned.  In this situation, many women who conceive while on psychotropic medications decide to abruptly stop their medications when they discover they are pregnant.  While this may seem like the safest option, in terms of protecting the developing fetus, we have data demonstrating high rates of relapse in women who discontinue antidepressant medications or mood stabilizers proximate to conception.  We now have data (from several studies in non-pregnant populations) to indicate that the rate of medication discontinuation (abrupt vs. gradual) may also affect risk of relapse.

By |2015-08-13T11:01:51-04:00September 13th, 2010|Anxiety Disorders, Depressive Disorders, Medication, Pregnancy & Medications, Psychiatric Disorders During Pregnancy, Treatment|Comments Off on Discontinuation of Antidepressants: Slower is Better

Should SSRIs Be Tapered Prior To Delivery?

Increased muscle tone, jitteriness, sleep disturbance, irritability, feeding problems, mild respiratory distress and myoclonus have been reported as symptoms of a potential neonatal distress syndrome related to exposure to SSRIs in late pregnancy.  The average duration of symptoms reported is 48 hours.  It is estimated that between 25-30% of SSRI-exposed infants are at risk for this syndrome.  No treatment intervention is required.  Reassuringly, follow-up studies have shown that at 2, 4, 6, and 8 months SSRI-exposed infants are indistinguishable from control infants without known exposure.

By |2015-08-12T17:01:53-04:00September 8th, 2010|Anxiety Disorders, Depressive Disorders, Medication, Pregnancy & Medications, Psychiatric Disorders During Pregnancy, Treatment|Comments Off on Should SSRIs Be Tapered Prior To Delivery?

The Importance of Proper Dosing of Antidepressants during Pregnancy

Pregnancy and the postpartum period is a time of increased risk for depression.  Therefore, women who are treated with antidepressant medications must consider whether or not to stay on medication during pregnancy.  Despite reassuring data regarding the reproductive safety of various antidepressants, a woman may prefer not to continue medication during pregnancy due to concerns about long term effects of medication on the baby.  However, by discontinuing antidepressant medication, a woman increases her risk of depression during pregnancy.  This is a highly personal decision for women as the potential risks of continuing medication must be weighed against the possibility of relapse and the potential effects of untreated depression on the pregnancy and baby.

By |2015-08-12T16:58:36-04:00August 30th, 2010|Anxiety Disorders, Depressive Disorders, Medication, Pregnancy & Medications, Psychiatric Disorders During Pregnancy, Treatment|Comments Off on The Importance of Proper Dosing of Antidepressants during Pregnancy

Massage Therapy for Depression

There are currently 100 clinical trials registered on clinicaltrials.gov using massage as a treatment.  Six are listed for the indication of depression.  A small minority are focused specifically on treating depression or anxiety, while in many the effects of massage for patients with serious medical conditions are being explored.  Infant massage is also under study for developmental benefits.  The number of randomized trials for verified psychiatric disorders using massage as an intervention are limited to date.

By |2015-08-12T16:56:28-04:00August 23rd, 2010|Alternative & Complementary, Depressive Disorders, General, Treatment|Comments Off on Massage Therapy for Depression

Non-Pharmacologic Options for the Treatment of Antenatal Depression: A Quick Review

About 15% of women suffer from depression during pregnancy, and the rate of depressive illness is greater in women with pre-existing histories of depression.  While there are data to support the use of certain antidepressants during pregnancy, many women are reluctant to seek pharmacologic treatment during pregnancy and may benefit from efficacious non-pharmacologic options.  In a recent review article from Medscape, Christopher Tjoa and colleagues from the University of Pennsylvania summarize the literature assessing the efficacy of non-pharmacologic options for the treatment of antenatal depression.

By |2015-08-12T16:51:45-04:00July 27th, 2010|Depressive Disorders, Psychiatric Disorders During Pregnancy, Psychotherapy, Treatment|Comments Off on Non-Pharmacologic Options for the Treatment of Antenatal Depression: A Quick Review

Depression and Anxiety: Do They Impact Infertility Treatment?

Infertility affects an estimated 10-15% of couples of reproductive age.  Several studies have indicated that patients undergoing in vitro fertilization (IVF) experience high levels of stress, depression, and anxiety.  Multiple risk factors for anxiety and depression during infertility treatment have been identified; these include being female, age over 30, lower level of education, lack of occupational activity, a male cause for infertility, and infertility for 3-6 years.

By |2015-08-12T16:46:54-04:00June 30th, 2010|Anxiety Disorders, Depressive Disorders, Infertility and Mental Health, Outcomes|Comments Off on Depression and Anxiety: Do They Impact Infertility Treatment?
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