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    15 12, 2008

    Bipolar Disorder and PMS

    By |2016-03-28T13:38:38-04:00December 15th, 2008|New Research, PMS and PMDD|

    Premenstrual worsening of mood is common among women with depression, but little is known about how often women with bipolar disorder experience worsening of their mood premenstrually. In a study by Payne et al. (2007), premenstrual symptoms were reported by twice as many women diagnosed with mood disorders (mixture of  Bipolar Disorder and Major Depressive Disorder) than by women who did not have a psychiatric diagnosis (67.7% vs. 33.7%).  These results suggest that PMS symptoms are particularly common in women with bipolar disorder and major depressive disorder. However, this study involved women reporting prior experiences with PMS, which is not always as accurate as studies that involve prospective monitoring to obtain real-time reporting of PMS symptoms.  Such prospective studies of PMS in women with bipolar disorder are sparse and have inconsistent conclusions.

    7 03, 2008

    Bipolar Disorder and Pregnancy: Should Medications Be Discontinued?

    By |2016-03-28T13:38:38-04:00March 7th, 2008|New Research, Psychiatric Disorders During Pregnancy|

    As many of the traditional mood stabilizers used to treat bipolar disorder, including lithium and valproic acid, carry some teratogenic risk and the reproductive safety of other medications, including the atypical antipsychotic agents, has not been well-characterized, many women with bipolar disorder decide to discontinue their treatment during pregnancy. A new study from Dr. Adele Viguera and her colleagues at the Massachusetts General Hospital and the Emory University School of Medicine helps to better define the risks associated with discontinuing treatment during pregnancy.

    6 01, 2001

    Bipolar Disorder and Pregnancy

    By |2016-03-28T13:38:39-04:00January 6th, 2001|New Research, Psychiatric Disorders During Pregnancy|

    Unfortunately the mood stabilizers most commonly used to treat bipolar disorder (including lithium and valproic acid) can increase the risk of certain types of birth defects or congenital malformations in children exposed to these medications during the first trimester of pregnancy. For this reason, many women with bipolar disorder choose to discontinue maintenance treatment during pregnancy. However, we have observed very high rates of illness during pregnancy among these women who discontinue treatment; over half of the women relapse, most frequently during the first trimester.

    15 09, 2003

    Bipolar Disorder

    By |2015-08-24T15:52:30-04:00September 15th, 2003|

    September 1, 2003 from ObGynNews By Lee S. Cohen, M.D. As the use of anticonvulsants to treat bipolar illness has grown over the past decade, so has the number of women successfully treated with these [...]

    15 12, 2004

    Bipolar Disorder Drugs

    By |2015-08-24T15:52:39-04:00December 15th, 2004|

    December 2004, ObGyn News, By Lee S. Cohen, M.D. Two of the agents widely used to treat bipolar illness are established teratogens. Lithium is associated with a 0.05% risk of Ebstein's anomaly, a modest teratogenic [...]

    5 02, 2013

    What’s Worse for Pregnancy: Bipolar Disorder or the Medications Used to Treat It?

    By |2015-08-06T13:29:48-04:00February 5th, 2013|Psychiatric Disorders During Pregnancy|

    In studies of pregnant women with unipolar depression, it has been shown that untreated psychiatric illness in the mother may have a negative impact on pregnancy outcomes, influencing the length of gestation and birthweight.  There is far less data on pregnancy outcomes in women with bipolar disorder.  A recent Swedish study analyzes pregnancy outcomes in treated and untreated women with bipolar disorder and attempts to distinguish between the effects of medication versus the effects of untreated psychiatric illness in the mother.

    11 08, 2008

    New England Journal of Medicine Case Report: Postpartum Psychosis in a Woman with Bipolar Disorder

    By |2016-03-28T13:23:59-04:00August 11th, 2008|New Research, Postpartum Psychiatric Disorders|

    The most recent issue of the New England Journal of Medicine includes the presentation of a case from the Center for Women's Mental Health of a woman with bipolar disorder who developed postpartum psychosis after the birth of her child. The case highlights some of the clinical challenges in treating patients with bipolar disorder during pregnancy and the postpartum period and reviews the current literature on postpartum psychosis.

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