Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to the Massachusetts General Hospital Center for Women’s Mental Health, a perinatal and reproductive psychiatry information center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Atypical Antipsychotics: All pregnant women ages 18-45 are eligible to enroll in the registry. We are currently seeking both controls and those being treated with one or more of the following atypical antipsychotics:
  • Abilify (aripiprazole)
  • Clozaril (clozapine)
  • Fanapt (iloperidone)
  • Geodon (ziprasidone)
  • Invega (paliperidone)
  • Latuda (lurasidone)
  • Risperdal (risperidone)
  • Saphris (asenapine)
  • Seroquel (quetiapine)
  • Zyprexa (olanzapine)
Register now by calling 1-866-961-2388 and help make the future better for many other women just like you. This study will involve 3 brief phone interviews over an 8-month period. The National Pregnancy Registry for Atypical Antipsychotics is dedicated to evaluating the safety of atypical antipsychotic medications that may be taken by women during pregnancy to treat a wide range of mood, anxiety, or psychiatric disorders. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics during pregnancy. For more information, please call 1-866-961-2388.

The MGH Center for Women’s Mental Health
Perinatal and Reproductive Psychiatry Program
Simches Research Building
185 Cambridge St Suite 2200
Boston, MA 02114

To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Latest News from our Blog

  • New Research from the CWMH: Armodafinil for Menopause-Related Fatigue

    July 6, 2015


    Several recent articles indicate that the burden of menopausal symptoms is greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase.  For most, the symptoms are manageable, but for a sizeable subset of midlife women, these symptoms can negatively ...

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  • Depression in Dads Affects Bonding

    June 30, 2015

    Credit: "Baby girl Hong Kong" by Foudeelau. Licensed CC BY-SA 3.0 via Wikimedia Commons -

    Multiple studies have shown that postpartum depression can interfere with bonding between the mother and her infant. While new fathers may also develop depression, little is known about how depression in the father affects bonding. A recent study from Sweden has taken a look at the association between maternal and paternal depressive symptoms and parental bonding ...

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  • Managing Sleep Problems in Menopausal Women: What Are the Options?

    June 29, 2015


    Peri- and post-menopausal women frequently complain of insomnia or poor sleep quality. Sleep disturbance is often attributed to nocturnal hot flashes; however, a recent study from researchers at Wayne State University School of Medicine suggests that a sizeable proportion of menopausal women may have a primary sleep disorder.  There are various options for managing insomnia ...

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  • ACOG Issues Opinion on Marijuana in Pregnant and Nursing Women

    June 26, 2015


    With many states now moving forward with  the legalization of medical marijuana, there seems to be a growing sense that marijuana is relatively safe and may, in some cases, be more attractive or effective than traditional pharmacologic interventions.  The use of marijuana in the United States appears to be increasing.  According to a nationwide survey, ...

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  • Adjunctive Treatment with Medroxyprogesterone in Women with Acute Mania

    June 24, 2015


    Women with bipolar disorder often experience fluctuating mood symptoms across the menstrual cycle, typically reporting an exacerbation of symptoms during the premenstrual phase of the cycle (Rasgon et al, 2003, 2005).  Other studies have indicated that women with bipolar disorder have more affective instability as they transition into the menopause, when there are pronounced fluctuations ...

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  • Brief Report: TMS for Depression During Pregnancy

    June 23, 2015

    Credit: Pregnant Woman from Wikimedia Commons

    Transcranial magnetic stimulation or TMS is similar to ECT but uses electromagnetic pulses to generate electrical current in specific regions of the brain that are known to modulate mood.  TMS is less likely to cause side effects and has thus been proposed as a possible alternative therapy for those suffering from treatment-resistant depression.  (You can ...

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