Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to the Massachusetts General Hospital Center for Women’s Mental Health, a perinatal and reproductive psychiatry information center. This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.
The National Pregnancy Registry for Atypical Antipsychotics: All pregnant women ages 18-45 are eligible to enroll in the registry. We are currently seeking both controls and those being treated with one or more of the following atypical antipsychotics:
  • Abilify (aripiprazole)
  • Clozaril (clozapine)
  • Fanapt (iloperidone)
  • Geodon (ziprasidone)
  • Invega (paliperidone)
  • Latuda (lurasidone)
  • Risperdal (risperidone)
  • Saphris (asenapine)
  • Seroquel (quetiapine)
  • Zyprexa (olanzapine)
Register now by calling 1-866-961-2388 and help make the future better for many other women just like you. This study will involve 3 brief phone interviews over an 8-month period. The National Pregnancy Registry for Atypical Antipsychotics is dedicated to evaluating the safety of atypical antipsychotic medications that may be taken by women during pregnancy to treat a wide range of mood, anxiety, or psychiatric disorders. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics during pregnancy. For more information, please call 1-866-961-2388.

The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Latest News from our Blog

  • In Brief: Group CBT for Perinatal Anxiety

    July 31, 2015


    Cognitive-behavioral therapy (CBT) is well-established as a treatment for anxiety disorders; however, few studies have examined the efficacy of CBT specifically tailored to address perinatal anxiety. A recent pilot study has explored the use of a group CBT intervention. The group included 10 pregnant or postpartum women who were recruited from a hospital setting and ...

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  • SSRIs for Vasomotor Symptoms and Bone Health

    July 28, 2015

    Photo by Christoph Lehmann

    Recent research has indicated that selective serotonin reuptake inhibitors (SSRIs) may be an effective option for the treatment of vasomotor symptoms associated with menopause. However, it has been documented in some recent observational studies that SSRIs are associated with an increased risk of bone loss in older patients (2, 4). Since postmenopausal women are already ...

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  • Augmentation with Quetiapine (Seroquel) for Women with PMDD

    July 27, 2015


    For women with premenstrual dysphoric disorder (PMDD), selective serotonin reuptake inhibitors (SSRIs) are the first line of pharmacological treatment. A significant body of evidence, including numerous double-blind, randomized studies, supports the effectiveness of SSRIs in reducing both the emotional, as well as physical symptoms, of PMS and PMDD. In general, women respond to low doses ...

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  • You Asked: Do Oral Contraceptives Cause Mood Swings or Depression?

    July 24, 2015


    Many women have concerns about the side effects of oral contraceptives (birth control pills). Potential side effects include bloating, breast tenderness, and weight gain. In addition, some women may experience depression or mood swings, side effects that may influence a woman’s decision to start taking an oral contraceptive (OC), particularly if she has a history ...

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  • Placentophagy: More Myth Than Miracle

    July 23, 2015


    Placentophagy.  That’s a fancy term for describing what some women do after giving birth.  Placentophagy refers to the act of eating the placenta after giving birth.  Almost all non-human placental mammals ingest their placentas after birth, and over the last decade, we have seen more women considering this option.  Health advocates claim that various hormones ...

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  • In Brief: Some Menopausal Symptoms Worse in Women with Depression

    July 17, 2015


    Nearly a third of postmenopausal women experience vaginal changes, including dryness, itching and pain during sex — symptoms related to the declining levels of estrogen occurring during the transition to menopause.  According to a study which included 745 postmenopausal women with vaginal symptoms, it appears that these symptoms may be more disruptive for women who ...

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