Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health

Welcome to the Massachusetts General Hospital Center for Women’s Mental Health, a perinatal and reproductive psychiatry information center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

We hope you find this website informative and we welcome your comments.

The National Pregnancy Registry for Atypical Antipsychotics: All pregnant women ages 18-45 are eligible to enroll in the registry. We are currently seeking both controls and those being treated with one or more of the following atypical antipsychotics:
  • Abilify (aripiprazole)
  • Clozaril (clozapine)
  • Fanapt (iloperidone)
  • Geodon (ziprasidone)
  • Invega (paliperidone)
  • Latuda (lurasidone)
  • Risperdal (risperidone)
  • Saphris (asenapine)
  • Seroquel (quetiapine)
  • Zyprexa (olanzapine)
Register now by calling 1-866-961-2388 and help make the future better for many other women just like you. This study will involve 3 brief phone interviews over an 8-month period. The National Pregnancy Registry for Atypical Antipsychotics is dedicated to evaluating the safety of atypical antipsychotic medications that may be taken by women during pregnancy to treat a wide range of mood, anxiety, or psychiatric disorders. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics during pregnancy. For more information, please call 1-866-961-2388.

The MGH Center for Women’s Mental Health
Perinatal and Reproductive Psychiatry Program
Simches Research Building
185 Cambridge St Suite 2200
Boston, MA 02114

To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Latest News from our Blog

  • Meta-Analysis:  Acupuncture Effective for Menopausal Vasomotor Symptoms

    April 17, 2015


    Over the last decade, various studies have evaluated the effectiveness of acupuncture for the treatment of menopausal vasomotor symptoms.  In a recent meta-analysis, studies that reported on the frequency or severity of hot flashes, menopause-related symptoms assessed using the Menopause Rating Scale (MRS), and quality of life (QoL) assessed using the Menopause-Specific Quality of Life ...

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  • How Does Mother’s Depression Affect the Fetal Brain? Look at the Amygdala

    April 15, 2015


    It is now widely accepted that there is an increased risk for depression among the children of mothers who suffer from depression.  Exactly how this vulnerability to depression is transmitted to the child is not precisely understood and is undoubtedly quite complicated.  Genetic factors clearly play an important role, but there are other important factors ...

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  • Postpartum Depression and Cigarette Smoking

    April 13, 2015


    A recent study examines the relationship between postpartum depression (PPD) and cigarette smoking.  The study sample consisted of 29,654 U.S. women who reported smoking in the 3 months prior to pregnancy and for whom data on PPD were available from the Pregnancy Risk Assessment Monitoring System (PRAMS).

    Read more
  • Restless Legs Syndrome Increases Risk of Perinatal Depression

    April 10, 2015


    Restless legs syndrome (RLS) occurs commonly during pregnancy and can sometimes casues significant sleep disturbance. A new study suggests that RLS may also increase the risk of perinatal depression.

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  • Parental Age and Risk of ADHD in Children

    April 7, 2015


    Many studies have examined the association between parental age and psychiatric illness in the children, including autism and schizophrenia.  In a recent case-control study from Finland, the authors identified 10,409 individuals with ADHD born between 1991 and 2005 from nationwide population-based registers.  Logistic regression was used to examine the association between parental age and ADHD ...

    Read more
  • Maternal Depression Leads to Risky Behaviors in Adolescent Children

    April 6, 2015


    Maternal depression has been identified as a risk factor for adolescent depression.  In addition, maternal depression appears to increase the risk of certain behavioral problems in children; however, it appears that the timing of exposure may play an important role in mediating the effects of maternal depression.  A recent study suggests that childhood exposure to maternal depression between ...

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  • Intergenerational Transmission of Depression: Telomere Shortening and Cortisol Reactivity in Girls at High Risk for Depression

    April 1, 2015


    In every cell, genetic material is contained within the double-stranded molecules of DNA called chromosomes. Every time a cell divides, the chromosomes are copied so that each new cell gets a copy of this genetic material.  However, the process isn’t perfect – a little bit of the end of the chromosome is lost each time ...

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  • You Asked:  Is It Safe to Take Melatonin During Pregnancy?

    March 30, 2015


    Many women experience some degree of sleep disturbance during pregnancy. For a significant number of women, the sleep disruption may be so severe as to require some type of intervention. In a previous post, we discussed the use of different types of medications to treat insomnia during pregnancy. While these drugs are highly effective, many women ...

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  • Low Vitamin D Levels Linked to Depression in Young Women

    March 26, 2015


    Vitamin D deficiency is more common than ever, and many experts are concerned that this deficiency may lead to a wide variety of health problems, including depression.

    Read more
  • You Asked: Should Lamotrigine (Lamictal) Dose Be Adjusted During Pregnancy?

    March 25, 2015

    For many women with bipolar disorder, lamotrigine (Lamictal) is an effective mood stabilizer.  Given its relatively favorable reproductive safety profile, lamotrigine is a reasonable option for women who require treatment with a mood stabilizer during pregnancy.

    Read more

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