|The Chronicity and Timing of Prenatal and Antenatal Maternal Depression and Anxiety on Child Outcomes at Age 5.|
Hentges RF, Graham SA, Fearon P, Tough S, Madigan S. Depress Anxiety. 2020 May 17.
In a prospective study of 1992 pregnant women, depression and anxiety were assessed. Child outcomes were assessed at age 5. Effect sizes were small for brief incidents of depression/anxiety and increased for intermittent and chronic problems (i.e., measured at three or more timepoints) compared with mothers who had never experienced clinical-level anxiety or depression.
Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis.
Levis B, McMillan D, Sun Y, He C, et al. nt J Methods Psychiatr Res. 2019 Dec;28(4):e1803. Among fully structured interviews, the MINI (15 studies, 2,532 participants, 342 major depression cases) identified depression more often than the CIDI (3 studies, 2,948 participants, 194 major depression cases; adjusted odds ratio [aOR] = 3.72).
The biological underpinnings of perinatal depressive symptoms: a multi-systems approach.
Nazzari S, Fearon P, Rice F, et al. J Affect Disord, May 2020.
Higher depressive symptoms during pregnancy were found to be associated with higher IL-6 levels, lower morning cortisol levels and a flatter cortisol diurnal slope during pregnancy.
Regional cerebral activity abnormality in pregnant women with antenatal depression.
Cheng B, Wang X, Zhou Y, et al. J Affect Disord, May 2020.
In women with antenatal depression, aberrant regional functional activities were observed, mainly located within the prefrontal-limbic circuit concerning multiple neural system abnormalities.
Antenatal psychological intervention for universal prevention of antenatal and postnatal depression: A systematic review and meta-analysis.
Yasuma N, Narita Z, Sasaki N, Obikane E, Sekiya J, Inagawa T, Nakajima A, Yamada Y, Yamazaki R, Matsunaga A, Saito T, Watanabe K, Imamura K, Kawakami N, Nishi D. J Affect Disord. 2020 May.
The meta-analysis showed a significant effect of antenatal psychological intervention on both antenatal and postnatal depression with moderate to high levels of heterogeneity. For subgroup analysis, a significant effect of a CB based approach on antenatal depression was found in an antenatal period, while non-significant results were shown on postnatal depression.
Effects of the COVID-19 pandemic on anxiety and depressive symptoms in pregnant women: a preliminary study.
F Duranku?, E Aksu. J of Maternal-Fetal & Neonatal Medicine, 2020.