|The Chronicity and Timing of Prenatal and Antenatal Maternal Depression and Anxiety on Child Outcomes at Age 5.
Hentges RF, Graham SA, Fearon P, Tough S, Madigan S. Depress Anxiety. 2020 May 17.
In a prospective study of 1992 pregnant women, depression and anxiety were assessed. Child outcomes were assessed at age 5. Effect sizes were small for brief incidents of depression/anxiety and increased for intermittent and chronic problems (i.e., measured at three or more timepoints) compared with mothers who had never experienced clinical-level anxiety or depression.
Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis.
Levis B, McMillan D, Sun Y, He C, et al. nt J Methods Psychiatr Res. 2019 Dec;28(4):e1803. Among fully structured interviews, the MINI (15 studies, 2,532 participants, 342 major depression cases) identified depression more often than the CIDI (3 studies, 2,948 participants, 194 major depression cases; adjusted odds ratio [aOR] = 3.72).
The biological underpinnings of perinatal depressive symptoms: a multi-systems approach.
Nazzari S, Fearon P, Rice F, et al. J Affect Disord, May 2020.
Higher depressive symptoms during pregnancy were found to be associated with higher IL-6 levels, lower morning cortisol levels and a flatter cortisol diurnal slope during pregnancy.
Regional cerebral activity abnormality in pregnant women with antenatal depression.
Cheng B, Wang X, Zhou Y, et al. J Affect Disord, May 2020.
In women with antenatal depression, aberrant regional functional activities were observed, mainly located within the prefrontal-limbic circuit concerning multiple neural system abnormalities.
Antenatal psychological intervention for universal prevention of antenatal and postnatal depression: A systematic review and meta-analysis.
Yasuma N, Narita Z, Sasaki N, Obikane E, Sekiya J, Inagawa T, Nakajima A, Yamada Y, Yamazaki R, Matsunaga A, Saito T, Watanabe K, Imamura K, Kawakami N, Nishi D. J Affect Disord. 2020 May.
The meta-analysis showed a significant effect of antenatal psychological intervention on both antenatal and postnatal depression with moderate to high levels of heterogeneity. For subgroup analysis, a significant effect of a CB based approach on antenatal depression was found in an antenatal period, while non-significant results were shown on postnatal depression.
Effects of the COVID-19 pandemic on anxiety and depressive symptoms in pregnant women: a preliminary study.
F Duranku?, E Aksu. J of Maternal-Fetal & Neonatal Medicine, 2020.