Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women between the ages of 18-45 with a history of psychiatric illness are eligible to enroll in the registry. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy.  We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants. For more information, please visit this page, call 1-866-961-2388 or e-mail

Course of ADHD in Pregnancy and the Postpartum

Are you pregnant? Do you have a history of ADHD?

If you are less than 20 weeks pregnant and have a history of ADHD, you may be eligible to take part in an observational research study for women maintaining, decreasing, or discontinuing psychostimulants during pregnancy and the postpartum. Women who participate will have 6 study visits that can be completed in-person at Massachusetts General Hospital or over the phone.

For more information, please call (617)726-2912 or email the study coordinator at

 EnBrace HR for MDD Relapse Prevention in         Women Trying to Conceive and Early Pregnancy:


Are you pregnant or planning a pregnancy? Do you feel depressed or have a history of depression? If you are less than 28 weeks pregnant or trying to conceive and have experienced depression now or in the past, you may be eligible to take part in a research study for the treatment of depression with a prenatal supplement. For more information, please visit this page, call Taylor at 617-643-9284 or email



Lifestyle Intervention Research Study Opportunity:

Are you pregnant or planning to become pregnant? Do you have a history of depression? Do you want to lose weight or have a healthier lifestyle? You may be eligible to participate in a research study evaluating a new lifestyle intervention for weight loss. Participants will receive 10 sessions of therapy at no cost to you.

If you are interested in participating or would like additional information, please call Samantha at 617-643-2076.


The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • Chasteberry for PMS and PMDD

    March 14, 2018

      Chasteberry, the fruit of the chaste tree or Vitex agnus castus, has long been touted as a remedy for a range of reproductive problems, including premenstrual symptoms or PMS.  Two recent publications have reviewed data on the use of Vitex agnus castus (VAC) for the treatment of premenstrual syndrome and premenstrual dysphoric disorder (PMDD) and ...

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  • Hormonal Contraceptives and Risk for Depression and Suicide

    March 13, 2018

      Many women have concerns about the side effects of hormonal contraceptives, including oral contraceptives, depot preparations, and hormonal IUDs and vaginal rings.  Potential side effects include bloating, breast tenderness, and weight gain. In addition, some women may experience depression or mood swings, side effects that may be particularly concerning to women with histories of depression. ...

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  • Weekly Roundup for March 9, 2018: Recent Publications in Women’s Mental Health

    March 10, 2018

    The first publication on the list, from Letourneau and colleagues, is a thorough review of interventions for antenatal and postpartum depression, many of them leading to improvements in parenting and child development.   Ruta Nonacs, MD PhD The effect of perinatal depression treatment for mothers on parenting and child development: A systematic review. Letourneau NL, Dennis CL, Cosic ...

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  • In Brief: Carbs in Your Diet Do Not Increase Your Risk for PMS

    March 8, 2018

      It is recommended that women with premenstrual symptoms (PMS) switch to a diet including more complex carbohydrates and less sugar in order to alleviate their symptoms.  While these dietary modifications may be helpful, a recent study indicates that carbohydrates in the diet is not associated with a woman’s risk of developing PMS symptoms.   In this study, researchers ...

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  • Are Mood and Anxiety Disorders More Common in Women with Polycystic Ovarian Syndrome?

    March 7, 2018

    Polycystic ovary syndrome (PCOS) is a common hormonal disorder, affecting about 10% of reproductive aged women. It is also the most common cause of infertility in younger women; however, many women are unaware they have PCOS until they experience problems with fertility.  In our clinic, where we see women with mood and anxiety disorders, many ...

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  • Perinatal Suicide: Highest Risk Occurs at 9 to 12 Months Postpartum

    March 6, 2018

      Even as perinatal mood and anxiety disorders have garnered more attention over the past several years, the most feared consequence of these disorders, suicide, remains a phenomenon that requires greater understanding. While suicide is a leading cause of death in perinatal women, suicide during pregnancy or the postpartum period is often underreported and under-researched. As ...

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