Every week we review the most recent publications in women’s mental health, covering topics related to premenstrual symptoms, perinatal mood and anxiety disorders, use of medications in pregnant and breastfeeding women, perinatal substance use, and menopausal mental health. 

For more detailed descriptions of many of these topics, you can sign up to receive our weekly CWMH NEWSLETTER which comes out every Thursday.  

And don’t forget to visit ESSENTIAL READS – a curated selection of up-to-date and clinically relevant articles in women’s mental health.

Ruta Nonacs, MD PhD


Clinical correlates of women endorsing premenstrual suicidal ideation: a cross-sectional study.

Carlini SV, Weiss SJ, Mordukhaev L, Jacob S, Flynn HA, Deligiannidis KM.

Biopsychosoc Med. 2022 Nov 8;16(1):23.

Of 153 participants endorsing premenstrual symptoms, 41 (27%) reported new or worsening concurrent premenstrual passive or active SI. Women who reported PMSI were significantly more likely to be single, unemployed, and childless as well as significantly more likely to report interference from premenstrual symptoms, histories of psychiatric hospitalization, adverse childhood events, suicide attempts, and current and past depression and anxiety compared to women without PMSI.



No articles this week



Culturally sensitive psychotherapy for perinatal women: A mixed methods study.

Singla DR, Hossain S, Andrejek N, Cohen MJ, Dennis CL, Kim J, La Porte L, Meltzer-Brody SE, Puerto Nino A, Ravitz P, Schoueri-Mychasiw N, Silver R, Vigod SN, Zibaman M, Schiller CE.

J Consult Clin Psychol. 2022 Oct;90(10):770-786.

Almost all providers and clinical leads reported insufficient training to deliver culturally sensitive psychotherapy. The most-endorsed challenge for participants and providers was apprehension to bring up issues of race and ethnicity during treatment.

The Relationship Between a Lifetime History of Sexual Victimization and Perinatal Depression: A Systematic Review and Meta-Analysis.

Lombardi BN, Jensen TM, Parisi AB, Jenkins M, Bledsoe SE.

Trauma Violence Abuse. 2023 Jan;24(1):139-155.

Women with a lifetime history of sexual victimization had 51% greater odds of experiencing PND relative to women with no history of sexual victimization (OR = 1.51, 95% CI [1.35, 1.67]).



Duloxetine Exposure During Pregnancy and the Risk of Offspring Being Born Small for Gestational Age or Prematurely: A Nationwide Danish and Swedish Safety Study.

Ankarfeldt MZ, Petersen J, Andersen JT, Fernandes MFS, Li H, Motsko SP, Fast T, Jimenez-Solem E. Drugs Real World Outcomes. 2022 Nov 10.

Duloxetine exposure during pregnancy is unlikely to increase the risk of small for gestational age.



Effect of internet-based cognitive behaviour therapy among women with negative birth experiences on mental health and quality of life – a randomized controlled trial.

Sjömark J, Svanberg AS, Larsson M, Viirman F, Poromaa IS, Skalkidou A, Jonsson M, Parling T. BMC Pregnancy Childbirth. 2022 Nov 12;22(1):835.

The ICBT intervention did not show superiority treatment as usual as both groups showed similar beneficial trajectories on several outcomes up to 1 year follow-up.

Depression and post-traumatic stress disorder after perinatal loss in fathers: A systematic review.

Lamon L, De Hert M, Detraux J, Hompes T. Eur Psychiatry. 2022 Oct 28;65(1):e72.

Some studies showed an increased risk of depressive and PTS symptoms in fathers after perinatal loss. However, many study results did not show significant differences, symptoms generally decreased over time, and the majority of studies showed higher levels of depressive and PTS symptoms in mothers, compared with fathers.



No articles this week



Association of Prepregnancy Substance Use and Substance Use Disorders with Pregnancy Timing and Intention.

Coy KC, Ko JY, Ondersma SJ, Gilstad-Hayden K, Zapata LB, Chang G, Yonkers K. J Womens Health (Larchmt). 2022 Nov;31(11):1630-1638.

Prepregnancy substance use was associated with a reduced likelihood of a well-timed (aPR 0.85; 95% CI: 0.77-0.93) and intended (aPR 0.80; 95% CI: 0.72-0.89) pregnancy; similarly, any SUD was associated with a reduced likelihood of a well-timed (aPR 0.66; 95% CI: 0.55-0.80) and intended (aPR 0.79; 95% CI: 0.67-0.93) pregnancy.

The impact of physical activity intervention on perinatal depression: A systematic review and meta-analysis.

He L, Soh KL, Huang F, Khaza’ai H, Geok SK, Vorasiha P, Chen A, Ma J. J Affect Disord. 2022 Oct 28;321:304-319.

indicated physical activity specifically targeted at pregnant women could reduce depression risk and severity.

Characteristics of Individuals in the United States Who Used Opioids During Pregnancy.

Nguyen RHN, Knapp EA, Li X, Camargo CA, Conradt E, Cowell W, Derefinko KJ, Elliott AJ, Friedman AM, Khurana Hershey GK, Hofheimer JA, Lester BM, McEvoy CT, Neiderhiser JM, Oken E, Ondersma SJ, Sathyanarayana S, Stabler ME, Stroustrup A, Tung I, McGrath M.

J Womens Health (Larchmt). 2022 Nov 9.

Maternal depression was associated with increased odds of opioid use during pregnancy by more than two-fold (adjusted odds ratio 2.42, 95% confidence interval: 1.95-3.01).



Perinatal maternal mental health and amygdala morphology in young adulthood.

Guma E, Andrýsková L, Brázdil M, Chakravarty MM, Mare?ková K. Prog Neuropsychopharmacol Biol Psychiatry. 2022 Nov 10:110676.

Greater maternal anxiety/co-dependence after birth was significantly associated with lower volume and non-significantly associated with surface area of the amygdala in young adulthood. Postnatal depression did not impact amygdala volume.

Effects of maternal trauma and associated psychopathology on atypical maternal behavior and infant social withdrawal six months postpartum.

Burtchen N, Alvarez-Segura M, Urben S, Giovanelli C, Mendelsohn AL, Guedeney A, Schechter DS. Attach Hum Dev. 2022 Nov 13:1-27.

Maternal trauma was correlated with atypical maternal behavior (AMB) and infant social withdrawal. Maternal PTSD, MDD, and comorbid PTSD/MDD predicted increased AMB, but only maternal MDD was predictive of infant social withdrawal.

The association between maternal symptoms of depression and hair glucocorticoids in infants across the perinatal period.

Karl M, Huth V, Schälicke S, Müller-Stark C, Weise V, Mack JT, Kirschbaum C, Weidner K, Garthus-Niegel S, Steudte-Schmiedgen S. Psychoneuroendocrinology. 2022 Oct 17;147:105952. doi: 10.1016/j.psyneuen.2022.105952.

Maternal depressive symptoms during pregnancy are associated with dysregulated infants’ hair cortisol levels mainly incorporated in the intrauterine period which, in turn, might contribute to increased susceptibility for later diseases. However, no relationship was observed in infants’ hair samples related to postpartum depressive symptoms.



No articles this week



No articles this week


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