PMS AND PMDD

INFERTILITY AND MENTAL HEALTH

The available data suggested that conception with ART was associated with lower incidence of postpartum depressive symptoms, especially when follow-up lasted over 3 months.

Acceptance and commitment therapy adapted for women with infertility: a pilot study of the Infertility ACTion program – PubMed

This acceptance and commitment therapy-based self-guided program proved to be an acceptable treatment for infertility-related distress.

Spontaneous miscarriage and social support in predicting risks of depression and anxiety: a cohort study in UK Biobank.

For participants with 1, 2, and ?3 spontaneous miscarriages, hazard ratios (95% confidence intervals) for depression were 1.10 (1.02-1.19), 1.31 (1.14-1.50), and 1.40 (1.18-1.67), respectively (P trend <.001), compared with participants without a history of spontaneous miscarriage. For anxiety, the hazard ratios (95% confidence intervals) were 1.07 (1.00-1.15), 1.04 (0.90-1.19), and 1.21 (1.02-1.44), respectively (P trend=.01).

PSYCHIATRIC ILLNESS DURING PREGNANCY

specialized partial hospitalization treatment for individuals with moderate to severe psychiatric illness can be effectively provided via telehealth, thus offering improved convenience, accessibility, and safety without compromising care. We conclude that remotely administered group psychotherapy is an effective intervention for women with moderate to severe PMADs.

Increasing Access To Perinatal Mental Health Care: The Perinatal Psychiatry Access Program Model – PubMed

Access programs implementeD program components, including telephone consultation with a perinatal psychiatry expert, one-time patient-facing consultation with a perinatal psychiatry expert, resource and referral to perinatal professionals or patients, trainings for perinatal professionals, and practice-level technical assistance. Characterizing population-based intervention models, such as perinatal psychiatry access programs, that address perinatal mental health conditions is a needed step toward evaluating and improving programs’ implementation, reach, and effectiveness.

Examining racial/ethnic inequities in treatment participation among perinatal individuals with depression – PubMed

Minoritized perinatal individuals had significantly lower odds of treatment referral (aOR = 0.48;95% CI = 0.27-0.88) than their non-Hispanic white (NHW) counterparts. There were no statistically significant differences in the odds of treatment initiation (aOR = 0.64 95% CI:0.36-1.2) or continuation of treatment (aOR = 0.54;95% CI = 0.28-1.1) by race/ethnicity.

Dysregulated placental expression of kynurenine pathway enzymes is associated with inflammation and depression in pregnancy – PubMed

This study indicates that in women with depression during pregnancy, there is evidence of a compromised placental environment, featuring low expression of critical kynurenine pathway enzymes and increased levels of plasma cytokines and the dysregulated kynurenine metabolite pattern.

Attention-Deficit Hyperactivity Disorder (ADHD) Medication Use Trajectories Among Women in the Perinatal Period – PubMed

Approximately 60% of women discontinued or interrupted their ADHD medication around pregnancy, and those who continued differed in sociodemographic and clinical factors that may reflect more severe ADHD.

Perinatal Mental Health: The Need For Broader Understanding And Policies That Meet The Challenges

MEDICATIONS AND PREGNANCY

Concentrations of Fluoxetine Enantiomers Decline During Pregnancy and Increase After Birth – PubMed

These data do not support a recommendation for routine plasma concentration monitoring or CYP2D6 pharmacogenetic testing for pregnant people treated with FLX; however, monitoring for symptom relapse is recommended because of declining plasma drug concentrations.

POSTPARTUM PSYCHIATRIC ILLNESS

Individuals experiencing postpartum depressive symptoms are less likely to utilize contraception after giving birth.

Association of Perinatal Depression and Postpartum Contraception Intent, Choice, and Actual Use – PubMed

Perinatal individuals with persistent depressive symptoms at 5-7 months postpartum reported greater use of less-effective contraception methods than originally planned.

The cost-effectiveness of zuranolone versus selective serotonin reuptake inhibitors for the treatment of postpartum depression in the United States – PubMed

What is more cost-effective for treating adults with PPD?

BREASTFEEDING

D-MER prevalence may be lower than previously reported. Patients with likely D-MER appear to have lower breastfeeding self-efficacy and higher depression scores. Those with preexisting mood disorders may be at higher risk of experiencing D-MER.

PERINATAL SUBSTANCE USE

Increasing data supporting use of a high-dose initiation regimen in the nonpregnant population. This retrospective case series describes six individuals with OUD who underwent high-dose buprenorphine initiation in pregnancy.

MATERNAL MENTAL HEALTH AND CHILD OUTCOMES

MENOPAUSE AND MENTAL HEALTH

OTHER TOPICS IN WOMEN’S MENTAL HEALTH

Having been diagnosed with PCOS is associated with a markedly increased risk of obesity and sleeping, sexual and eating disorders, also after accounting for factors shared between sisters and early-life conditions.