The comorbidity of Axis I disorders in depressed pregnant women.

Dindo L, Elmore A, O’Hara M, Stuart S.  Arch Womens Ment Health. 2017 Aug 25.

Researchers observed high rates of anxiety disorders among women both with and without current major depression, although depressed women reported higher rates of generalized anxiety disorder and post-traumatic stress disorder.

Maternal posttraumatic stress disorder during the perinatal period and child outcomes: A systematic review.

Cook N, Ayers S, Horsch A.  J Affect Disord. 2018 Jan 1;225:18-31.

Maternal postpartum PTSD is associated with low birth weight and lower rates of breastfeeding. Evidence for an association between maternal PTSD and preterm birth, fetal growth, head circumference, mother-infant interaction, the mother-infant relationship or child development is contradictory. Associations between maternal PTSD and infant salivary cortisol levels, and eating/sleeping difficulties are based on single studies, so require replication.

Pregnancy and the Acceptability of Computer-Based Versus TraditionalMental Health Treatments.

Hantsoo L, Podcasy J, Sammel M, Epperson CN, Kim DR.  J Womens Health (Larchmt). 2017 Oct;26(10):1106-1113.

While computer-based therapies were acceptable to most pregnant women in this sample, traditional talk therapy was the preferred option.

Association between Duration of Folic Acid Supplementation during Pregnancy and Risk of Postpartum Depression.

Yan J, Liu Y, Cao L, Zheng Y, Li W, Huang G.Nutrients. 2017 Nov 2;9(11).  Free Article

In this study of Chinese women, the use of folic acid supplements for more than 6 months during pregnancy was associated with a 25% reduction in risk for PPD (as compared to riks of PPD in women who used folic acid for less than 6 months).

Reproductive Affective Disorders: A Review of the Genetic Evidence for Premenstrual Dysphoric Disorder and Postpartum Depression.

McEvoy K, Osborne LM, Nanavati J, Payne JL.  Curr Psychiatry Rep. 2017 Oct 30;19(12):94.

Evidence is stronger for the genetic basis for PPD, with positive associations found in family studies and in several genes associated with major depression as well as genes involved in estrogen signaling but only when PPD onset is shortly after delivery. Epigenetic biomarkers on genes responsive to estrogen have also been found to predict PPD.

Development of a women’s mental health curriculum and evolution to a Women’s Mental Health Area of Concentration in a psychiatry residency program.

Gopalan P, Glance J, Valpey R, Joseph H, Shenai N.  Arch Womens Ment Health. 2017 Oct 27.

Opioid Addiction in Pregnancy: Does Depression Negatively Impact Adherence With Prenatal Care?

Hensley L, Sulo S, Kozmic S, Parilla BV.  J Addict Med. 2017 Oct 24.

In this study, 45/74 (60.8%) of the opioid-dependent pregnant patients were either diagnosed with depression (n?=?41), anxiety (n?=?2), or scored >10 on the Edinburgh Prenatal Depression Scale (n?=?1). Patients with a diagnosis of depression were significantly less adherent with prenatal care; 80% adherent (73% vs 93%; P?=?0.03), 90% adherent (62% vs 93%; P?=?0.003).

The association of stillbirth with depressive symptoms 6-36 months post-delivery.

Hogue CJ, Parker CB, Willinger M, Temple JR, Bann CM, Silver RM, Dudley DJ, Moore JL, Coustan DR, Stoll BJ, Reddy UM, Varner MW, Saade GR, Conway D, Goldenberg RL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Stillbirth Collaborative Research Network Writing Group.  Paediatr Perinat Epidemiol. 2015 Mar;29(2):131-43.

Depression was about twice as likely after stillbirth as compared to giving birth to a liveborn infant.  

Examining pathways linking maternal depressive symptoms in infancy to children’s behavior problems: The role of maternal unresponsiveness and negative behaviors.

Norcross PL, Leerkes EM, Zhou N.

Infant Behav Dev. 2017 Oct 5;49:238-247.

Parenting mediates the impact of maternal depression on child internalizing symptoms.

Kuckertz JM, Mitchell C, Wiggins JL. Depress Anxiety. 2017 Sep 29.

This study suggests a bidirectional relationship between child and maternal internalizing psychopathology that is partially explained by depressed mothers’ greater use of psychological aggression toward their children.

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