We have seen articles over the last decade which suggest that while some women experience clinically significant psychological symptoms after early pregnancy loss, the vast majority of women manage to navigate this stressful life event without serious after effects.  A small study from Farren and colleagues suggests that PTSD is quite common among women who have experienced either a miscarriage or ectopic pregnancy, with 28% meeting the criteria for probable PTSD at 1 month and 38% at 3 months.  Further study in larger populations will help to determine which women are the most vulnerable in this setting.

We hope that everybody has a happy and healthy Thanksgiving holiday.  

Ruta Nonacs, MD PhD


Post-traumatic stress, anxiety and depression following miscarriage or ectopic pregnancy: a prospective cohort study.

Farren J, Jalmbrant M, Ameye L, Joash K, Mitchell-Jones N, Tapp S, Timmerman D, Bourne T.  BMJ Open. 2016 Nov 2;6(11):e011864.   Free Article


Sex-Specific Alterations of White Matter Developmental Trajectories in Infants With Prenatal Exposure to Methamphetamine and Tobacco.

Chang L, Oishi K, Skranes J, Buchthal S, Cunningham E, Yamakawa R, Hayama S, Jiang CS, Alicata D, Hernandez A, Cloak C, Wright T, Ernst T.  JAMA Psychiatry. 2016 Nov 9. [Epub ahead of print]


Maternal depressive symptoms and early childhood cognitive development: a meta-analysis.

Liu Y, Kaaya S, Chai J, McCoy DC, Surkan PJ, Black MM, Sutter-Dallay AL, Verdoux H, Smith-Fawzi MC.  Psychol Med. 2016 Nov 11:1-10. [Epub ahead of print]


An international position paper on mother-infant (perinatal) mental health, with guidelines for clinical practice.

Brockington I, Butterworth R, Glangeaud-Freudenthal N. Arch Womens Ment Health. 2016 Nov 8. [Epub ahead of print]


Distinctive gene expression profile in women with history of postpartum depression.

Landsman A, Aidelman R, Smith Y, Boyko M, Greenberger C.  Genomics. 2016 Nov 2. [Epub ahead of print]


Postpartum Depressive Symptoms Following Consecutive Pregnancies: Stability, Change, and Mechanisms.

Schetter CD, Saxbe D, Cheadle A, Guardino C.  Clin Psychol Sci. 2016 Sep;4(5):909-918.


Screening for and Treating Postpartum Depression and Psychosis: A Cost-Effectiveness Analysis.

Wilkinson A, Anderson S, Wheeler SB.  Matern Child Health J. 2016 Nov 10. [Epub ahead of print]


Variation and ethnic inequalities in treatment of common mental disorders before, during and after pregnancy: combined analysis of routine and research data in the Born in Bradford cohort.

Prady SL, Pickett KE, Gilbody S, Petherick ES, Mason D, Sheldon TA, Wright J.  BMC Psychiatry. 2016 Apr 12;16:99. PMID:  Free Article


Parental Relationship with Twins from Pregnancy to 3 Months: The Relation Among Parenting Stress, Infant Temperament, and Well-Being.

Prino LE, Rollè L, Sechi C, Patteri L, Ambrosoli A, Caldarera AM, Gerino E, Brustia P.  Front Psychol. 2016 Oct 21;7:1628.  Free Article


Antenatal and Postnatal Symptoms of Depression: Evidence from Growing Up in New Zealand.

Underwood L, Waldie KE, D’Souza S, Peterson ER, Morton SM.  Matern Child Health J. 2016 Nov 11. [Epub ahead of print]


Correlates of postpartum depression in first time mothers without previous psychiatric contact.

Sylvén SM, Thomopoulos TP, Kollia N, Jonsson M, Skalkidou A.  Eur Psychiatry. 2016 Nov 9;40:4-12.


The analysis of anxiety and mood in healthy late-reproductive-stage women with regard to hormonal and genetic factors.

Jurczak A, Szkup M, Grzywacz A, Safranow K, Grochans E.  Arch Womens Ment Health. 2016 Dec;19(6):1141-1148.

In this group of Polish women, there were no statistically significant differences in the mood and the mean levels of anxiety depending on the presence of the polymorphisms analyzed in this study.


Vulnerability to intimate partner violence and poor mental health in the first 4-year postpartum among mothers reporting childhood abuse: an Australian pregnancy cohort study.

Gartland D, Woolhouse H, Giallo R, McDonald E, Hegarty K, Mensah F, Herrman H, Brown SJ.  Arch Womens Ment Health. 2016 Dec;19(6):1091-1100.


Risk of gestational hypertension and preeclampsia in women who discontinued or continued antidepressant medication use during pregnancy.

De Ocampo MP, Araneta MR, Macera CA, Alcaraz JE, Moore TR, Chambers CD.  Arch Womens Ment Health. 2016 Dec;19(6):1051-1061.


Risks and benefits of psychotropic medication in pregnancy: cohort studies based on UK electronic primary care health records.

Petersen I, McCrea RL, Sammon CJ, Osborn DP, Evans SJ, Cowen PJ, Freemantle N, Nazareth I.  Health Technol Assess. 2016 Mar;20(23):1-176. Free Article


Maternal depressed mood moderates the impact of infant sleep on mother-infant bonding.

Hairston IS, Solnik-Menilo T, Deviri D, Handelzalts JE.  Arch Womens Ment Health. 2016 Dec;19(6):1029-1039.


Postpartum psychiatric emergency visits: a nested case-control study.

Barker LC, Kurdyak P, Fung K, Matheson FI, Vigod S.  Arch Womens Ment Health. 2016 Dec;19(6):1019-1027.


Predictors of birth-related post-traumatic stress symptoms: secondary analysis of a cohort study.

Furuta M, Sandall J, Cooper D, Bick D.  Arch Womens Ment Health. 2016 Dec;19(6):987-999.


Use of selective serotonin reuptake inhibitors (SSRIs) in women delivering liveborn infants and other women of child-bearing age within the U.S. Food and Drug Administration’s Mini-Sentinel program.

Andrade SE, Reichman ME, Mott K, Pitts M, Kieswetter C, Dinatale M, Stone MB, Popovic J, Haffenreffer K, Toh S.  Arch Womens Ment Health. 2016 Dec;19(6):969-977.


Peripartum changes in social support among women with and without anxiety and depressive disorders prior to pregnancy: a prospective-longitudinal study.

Asselmann E, Wittchen HU, Erler L, Martini J.  Arch Womens Ment Health. 2016 Dec;19(6):943-952.


Effects of Human Maternal Placentophagy on Maternal Postpartum Iron Status: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.

Gryder LK, Young SM, Zava D, Norris W, Cross CL, Benyshek DC.  J Midwifery Womens Health. 2016 Nov 3.


Psychopathology and parenting: An examination of perceived and observed parenting in mothers with depression and PTSD.

Muzik M, Morelen D, Hruschak J, Rosenblum KL, Bocknek E, Beeghly M.  J Affect Disord. 2017 Jan 1;207:242-250.


Effects of prenatal and postnatal maternal emotional stress on toddlers’ cognitive and temperamental development.

Lin Y, Xu J, Huang J, Jia Y, Zhang J, Yan C, Zhang J. J Affect Disord. 2017 Jan 1;207:9-17.


Chronobiology, sleep-related risk factors and light therapy in perinatal depression: the “Life-ON” project.

Baiardi S, Cirignotta F, Cicolin A, Garbazza C, D’Agostino A, Gambini O, Giordano A, Canevini M, Zambrelli E, Marconi AM, Mondini S, Borgwardt S, Cajochen C, Rizzo N, Manconi M.  BMC Psychiatry. 2016 Nov 4;16(1):374.  Free Article


Fetal antiepileptic drug exposure and cognitive outcomes.

Bromley RL, Baker GA.  Seizure. 2016 Oct 14. [Epub ahead of print] Review.

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