Mass General Hospital

Harvard Medical School

Tag Archives | women’s mental health

You Asked: Can Modafinil (Provigil) be Used to Treat Menopausal Fatigue

Each year in the United States, the menopause transition is experienced by 1.5 million women.  With this change in the hormonal milieu comes troublesome symptoms, including vasomotor symptoms, decreased libido, insomnia, changes in mood, fatigue, and changes in cognitive functioning.   Fatigue is a common problem among middle-aged women; however, it has received less attention […]

Continue Reading · 0

New Research from the CWMH: Armodafinil for Menopause-Related Fatigue

Several recent articles indicate that the burden of menopausal symptoms is greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase.  For most, the symptoms are manageable, but for a sizeable subset of midlife women, these symptoms can negatively […]

Continue Reading · 0

SSRI Antidepressants and PPHN: Much Lower Risk Than Previously Reported

In 2006, Chambers and colleagues published an article linking selective serotonin reuptake inhibitor (SSRI) antidepressant use during late pregnancy to an increased risk of persistent pulmonary hypertension in the newborn (PPHN). PPHN is a cardiovascular syndrome typically occurring in full-term or near-term infants. After birth, the infant’s pulmonary vascular resistance remains high; blood is shunted […]

Continue Reading · 0

What is S-Equol? Does It Really Work for Menopausal Symptoms?

Approximately 70% of all women experience hot flashes and/or night sweats (also called vasomotor symptoms or VMS) during the menopause transition.  Although estrogen-containing hormone therapy is highly effective in managing these symptoms, various studies have raised concerns regarding the risks associated with prolonged use of hormone therapy and many women now use other non-hormonal options to manage their symptoms, including over-the-counter complementary and alternative medicines (CAMs), including soy isoflavones, black cohosh, and omega-3 fatty acids.  However, the data regarding the effectiveness of these alternative treatments has been mixed.

Continue Reading · 0

Hormone Replacement Therapy: Some Risk But No Impact on Mortality

While there are concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain settings.  A study presented this week at the Endocrine Society’s annual meeting which analyzed data from 43 randomized clinical trials suggests that menopausal hormone-replacement therapy does not appear to affect mortality either positively or negatively.

Continue Reading · 0

Menopausal Vasomotor Symptoms Last Longer than Five Years for Most Women

Up to 80% of women experience vasomotor symptoms (VMS) as they transition into the menopause phase. While clinical guidelines suggest that VMS typically last from 6 months to 2 years, we often see women with VMS lasting for a much longer period of time. To more accurately assess the duration of VMS in perimenopausal women, researchers analyzed data from 1449 women included in the Study of Women’s Health Across the Nation (SWAN), an observational study of women entering menopause.  Here is a summary of the key findings:

Continue Reading · 0

Happy New Year: Let’s Start By Taking a Look Back to 2014

2014 was a huge year in the field of Reproductive Psychiatry.  Never before have we seen so many articles published in this specialty.  Much attention has focused on the reproductive safety of psychotropic medication; however, we have seen an increased interest in the mental health of women and a greater appreciation of how psychiatric illness in the mother may affect the entire family, including her unborn child and family.

Continue Reading · 0

Breastfeeding and Anti-Epileptic Medications

Because breastfeeding has many psychological and medical benefits for both the mother and her child, many women would like to breastfeed. However, all medications taken by the mother are secreted into the breast milk. While various studies have addressed the short-term safety of antiepileptic drugs (AEDs) in nursing infants, none have systematically assessed the long-term effects of exposure to these drugs on cognitive development.

Continue Reading · 0