teratogenic risk

Which is Safer for the Treatment of Opioid Use Disorder During Pregnancy: Buprenorphine or Methadone?

In this large cohort study analyzing data from publicly insured Medicaid beneficiaries, the overall risk of malformations was lower with buprenorphine than with methadone.

By Ruta Nonacs, MD PhD|2024-05-16T06:55:02-04:00March 6th, 2024|Opioids, Perinatal Substance Use, Treatment|Comments Off

Should We Just Say No? Valproic Acid and Women of Childbearing Age

There have long been concerns regarding the use of the anticonvulsant valproate (Depakote) during pregnancy. First trimester use of valproate has been associated with a 3-5% risk of neural tube defects, as well as [...]

By MGH Center for Women's Mental Health|2016-06-16T23:14:25-04:00June 16th, 2016|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off