Over the years, we have seen a number of research studies which suggested a link between maternal smoking during pregnancy and adverse psychiatric outcomes in offspring, including increased risk for bipolar disorder, schizophrenia, and attention-deficit/hyperactivity disorder (ADHD). In a recent article published in JAMA Psychiatry, researchers reported on the results of a population-based cohort study […]
Tag Archives | preterm birth
More and more people are using electronic cigarettes. While e-cigarettes are often touted as being safer than tobacco-containing cigarettes, there is fierce debate among experts as to whether this is actually the case. There is also no evidence that e-cigarettes facilitate smoking cessation. A recent study suggests that many pregnant women — more than 40% […]
Given the number of younger women using atypical antipsychotic medications, we need more accurate data regarding the reproductive safety of these medications. To better understand the link between antipsychotic medication and medical conditions associated with pregnancy, including gestational diabetes and hypertension, researchers compared pregnancy outcomes in 1,021 pregnant women taking antipsychotic medication to outcomes in […]
Second-generation or “atypical” antipsychotics, such as olanzapine (Zyprexa), aripiprazole (Abilify), and risperidone (Risperdal), are used far more frequently than are the first-generation or “typical” antipsychotics, such as haloperidol (Haldol). This is largely because the newer agents are associated with fewer side effects and, as a result, have been used for a wider spectrum of illnesses, […]
You can find a more recent post on this topic here: Venlafaxine and Duloxetine: Pooled Analysis Shows No Increase in Risk of Malformations We receive a fair number of questions on the use of duloxetine during pregnancy. Duloxetine (sold in the United Sates under the brand name of Cymbalta) is a serotonin-norepinephrine reuptake inhibitor (SNRI) […]
Posttraumatic stress disorder (PTSD) is relatively common among pregnant and postpartum women. The lifetime prevalence of PTSD for women is about 10%. PTSD is most prevalent among women of childbearing age and PTSD symptoms are common during pregnancy. Earlier this year, we reported on a study which observed that women with a diagnosis of PTSD had an increased risk of preterm birth. The risk was particularly high in those women with diagnoses of both PTSD and a major depressive episode; these women had a 4-fold increased risk of preterm birth.
Women with psychiatric disorders represent an at-risk population for premature delivery and other obstetrical complications. This study assesses the association between omega-3 fatty acid use and length of gestation. In an unadjusted model, there was a significant increase of between 4 and 5 days (0.65 weeks; 0.00-1.25) in gestational length among the omega-3 users, although […]
With the advent of the newer, atypical antipsychotic medications, patients with psychotic disorders have been able to achieve greater symptom control with less disabling side effects. For women with schizophrenia, there has also been an increase in fertility rates over the last decade. Previous studies have suggested that women with schizophrenia, as compared to women with no psychiatric illness, are at increased risk for pregnancy and delivery complications, including low birthweight, intrauterine growth restriction, and preterm birth. However, most of these studies occurred at a time when the women were treated with older antipsychotic medications, and we cannot assume that these findings are relevant now, when women with schizophrenia are more commonly treated with the newer atypical antipsychotics and have much better control of their symptoms.
A recent study followed 29 mothers who gave birth to 35 premature children born before the 33rd week of pregnancy. The women were assessed within 2 weeks postpartum (T0), 2 weeks after hospitalization (T1), 6 months post-term (T2), and 18 months post-term (T3). The Impact of Event Scale (IES), General Health Questionnaire (GHQ) and State Anxiety Inventory (STAI-X1) were used to assess maternal mental health outcomes.
Posttraumatic stress disorder (PTSD) is relatively common among pregnant and postpartum women. The lifetime prevalence of PTSD for women is about 10%, with one-third of episodes lasting more than five years. Given the relatively high prevalence of PTSD in young women and the chronic nature of the illness, many women may experience PTSD symptoms during […]