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Tag Archives | preterm birth

Smoking During Pregnancy Not Associated with Severe Mental Illness in Offspring, But Other Risks Exist

Over the years, we have seen a number of research studies which suggested a link between maternal smoking during pregnancy and adverse psychiatric outcomes in offspring, including increased risk for bipolar disorder, schizophrenia, and attention-deficit/hyperactivity disorder (ADHD).  In a recent article published in JAMA Psychiatry, researchers reported on the results of a population-based cohort study […]

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Many Pregnant Women Unaware of the Risks of Electronic Cigarettes

More and more people are using electronic cigarettes.  While e-cigarettes are often touted as being safer than tobacco-containing cigarettes, there is fierce debate among experts as to whether this is actually the case.  There is also no evidence that e-cigarettes facilitate smoking cessation. A recent study suggests that many pregnant women — more than 40% […]

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Baby Belly from Wikimedia Commons

In Brief: Study Finds No Link Between Antipsychotics and Gestational Diabetes

Given the number of younger women using atypical antipsychotic medications, we need more accurate data regarding the reproductive safety of these medications. To better understand the link between antipsychotic medication and medical conditions associated with pregnancy, including gestational diabetes and hypertension, researchers compared pregnancy outcomes in 1,021 pregnant women taking antipsychotic medication to outcomes in […]

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Meta-Analysis: Antipsychotics and Pregnancy Outcomes

Second-generation or “atypical” antipsychotics, such as olanzapine (Zyprexa), aripiprazole (Abilify), and risperidone (Risperdal), are used far more frequently than are the first-generation or “typical” antipsychotics, such as haloperidol (Haldol). This is largely because the newer agents are associated with fewer side effects and, as a result, have been used for a wider spectrum of illnesses, […]

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You Asked: Is Duloxetine (Cymbalta) Safe To Use During Pregnancy?

You can find a more recent post on this topic here: Venlafaxine and Duloxetine: Pooled Analysis Shows No Increase in Risk of Malformations We receive a fair number of questions on the use of duloxetine during pregnancy.  Duloxetine (sold in the United Sates under the brand name of Cymbalta) is a serotonin-norepinephrine reuptake inhibitor (SNRI) […]

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PTSD in Veterans Increases Risk of Preterm Birth

Posttraumatic stress disorder (PTSD) is relatively common among pregnant and postpartum women. The lifetime prevalence of PTSD for women is about 10%.  PTSD is most prevalent among women of childbearing age and PTSD symptoms are common during pregnancy.  Earlier this year, we reported on a study which observed that women with a diagnosis of PTSD had an increased risk of preterm birth.  The risk was particularly high in those women with diagnoses of both PTSD and a major depressive episode; these women had a 4-fold increased risk of preterm birth.

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Credit: Hugrekk via flickr

New Research from the CWMH: Omega-3 Fatty Acids Increase Gestational Length

Women with psychiatric disorders represent an at-risk population for premature delivery and other obstetrical complications. This study assesses the association between omega-3 fatty acid use and length of gestation.  In an unadjusted model, there was a significant increase of between 4 and 5 days (0.65 weeks; 0.00-1.25) in gestational length among the omega-3 users, although […]

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Pregnancy Outcomes in Women with Schizophrenia

With the advent of the newer, atypical antipsychotic medications, patients with psychotic disorders have been able to achieve greater symptom control with less disabling side effects. For women with schizophrenia, there has also been an increase in fertility rates over the last decade.  Previous studies have suggested that women with schizophrenia, as compared to women with no psychiatric illness, are at increased risk for pregnancy and delivery complications, including low birthweight, intrauterine growth restriction, and preterm birth.  However, most of these studies occurred at a time when the women were treated with older antipsychotic medications, and we cannot assume that these findings are relevant now, when women with schizophrenia are more commonly treated with the newer atypical antipsychotics and have much better control of their symptoms.

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Anxiety and PTSD Associated with Preterm Birth

A recent study followed 29 mothers who gave birth to 35 premature children born before the 33rd week of pregnancy. The women were assessed within 2 weeks postpartum (T0), 2 weeks after hospitalization (T1), 6 months post-term (T2), and 18 months post-term (T3). The Impact of Event Scale (IES), General Health Questionnaire (GHQ) and State Anxiety Inventory (STAI-X1) were used to assess maternal mental health outcomes.

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