A new cohort study from Australia found that lithium use during pregnancy was linked to a two-fold increased risk of spontaneous preterm birth, along with higher risks of a large for gestational age infant and congenital cardiac malformations. We review how these findings compare with prior research and what they mean for women with bipolar disorder who are using — or considering — lithium during pregnancy.
Recent studies find no increase in the risk of major malformations with first-trimester Z-drug exposure, although small increases in risk of preterm birth and low birth weight have been reported.
Lithium use during pregnancy was associated with an increased risk of preterm birth and large for gestational age infants.
A large cohort study from Canada has observed that cannabis use during pregnancy was associated with increased risk of preterm birth, low birth weight and small-for-gestational age.
Treatment with buprenorphine versus methadone during pregnancy is associated with lower risk of preterm birth, low birth weight, small size for gestational age, and NAS.
Largest studies to date demonstrate statistically significant risk of preterm birth among women with active PTSD.
Prenatal cannabis exposure was associated with persisting vulnerability to psychopathology throughout early adolescence.
Prenatal opioid use is associated with increased maternal and infant mortality, prematurity, and poor neonatal outcomes.
Stress and worse pregnancy outcomes, interventions to reduce risk, parenting adolescents, dealing with social media.
The findings of this study do not suggest that prenatal antipsychotics exposure is associated with increased risk for ADHD, ASD, small for gestational age, or preterm birth.
