preterm birth

Risk of Preterm Birth and Respiratory Distress in Pregnancies with Prenatal Exposure to Antidepressants

From the OptumLabs Data Warehouse, researchers identified 226,932 singleton deliveries. Cases of antidepressant exposure were defined as pregnancies with prescription claims for antidepressants submitted between the last menstrual period and 35 weeks’ gestation.  To [...]

Maternal Anxiety and Adverse Perinatal Outcomes: Why We Need to Screen Women for Anxiety During Pregnancy

When providing information to patients regarding the use of medications during pregnancy, one key element of the decision-making process is an appraisal of the risks associated with untreated psychiatric illness in the mother.  While there [...]

Lithium and Anticonvulsant Mood Stabilizers: No Higher Risk for Adverse Pregnancy Outcomes

For women with bipolar disorder, choosing whether to maintain or discontinue treatment with a mood stabilizer during pregnancy is challenging.  This is a process which requires careful and thoughtful consideration, weighing the risk of adverse [...]

Smoking During Pregnancy Not Associated with Severe Mental Illness in Offspring, But Other Risks Exist

Over the years, we have seen a number of research studies which suggested a link between maternal smoking during pregnancy and adverse psychiatric outcomes in offspring, including increased risk for bipolar disorder, schizophrenia, and attention-deficit/hyperactivity [...]

PTSD in Veterans Increases Risk of Preterm Birth

Posttraumatic stress disorder (PTSD) is relatively common among pregnant and postpartum women. The lifetime prevalence of PTSD for women is about 10%.  PTSD is most prevalent among women of childbearing age and PTSD symptoms are common during pregnancy.  Earlier this year, we reported on a study which observed that women with a diagnosis of PTSD had an increased risk of preterm birth.  The risk was particularly high in those women with diagnoses of both PTSD and a major depressive episode; these women had a 4-fold increased risk of preterm birth.