Mass General Hospital

Harvard Medical School

Tag Archives | menopause

Transdermal Estradiol, But Not Oral Estrogens, Improves Sexual Function in Postmenopausal Women

  Sexual dysfunction is common among peri- and postmenopausal women and include a spectrum of problems, including low (or hypoactive) sexual desire, decreased satisfaction, and discomfort.   Reports indicate that the prevalence of hypoactive sexual desire ranges from 9% in naturally postmenopausal women up to 26% in younger surgically postmenopausal women.  A recent study compares the […]

Continue Reading · 0

In Brief: Night Sweats? Hot Flashes? Try Yoga

Yoga is frequently recommended as a treatment for menopause-related symptoms, including vasomotor symptoms and sleep disturbance; however, studies regarding its effectiveness have yielded mixed results. In a recent meta-anlsyis, researchers analyzed data from 13 randomized controlled trials with a total of 1306 participants. Compared with no treatment, yoga reduced total menopausal symptoms, and specifically led […]

Continue Reading · 0

In Brief: Hormone Replacement Has No Impact on Mortality in Women

While there have been concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain populations and that hormone replacement is appropriate in certain settings.  A recent study published in JAMA has focused on mortality rates in women treated with […]

Continue Reading · 0

Estrogen Receptor Modulator Raloxifene for Women with Schizophrenia

  Several years ago, we reviewed a paper suggesting that estrogen may have beneficial effects for women with schizophrenia.  In this study, women with schizophrenia were treated with estrogen in addition to their antipsychotic medications.  Adjunctive treatment with estrogen was associated with significant improvement in their positive symptoms (hallucinations, delusions), but the women experienced no […]

Continue Reading · 0

In Brief:  Traumatic Events in Childhood and Adolescence Increase Risk for Perimenopausal Depression

  Previous studies have indicated that depression during the perimenopausal transition is associated with various risk factors, including previous history of depression, poor physical health, and more severe perimenopausal symptoms.  A recent study (reviewed here) indicates that women who experienced multiple traumatic events during childhood or adolescence are more likely to experience depression during the […]

Continue Reading · 0

Weekly Roundup for MARCH 17, 2017: Recent Publications in Women’s Mental Health

  The most interesting article this week is from Dowlati and colleagues assessing the effectiveness of a nutritional supplement to decrease risk for postpartum blues.  While intriguing, it is not clear how effective this intervention will prove to be.   We will have a post on this paper next week.     Dowlati Y, Ravindran AV, […]

Continue Reading · 0
Photo by Christoph Lehmann

Vasomotor Symptoms and the Importance of Maintaining a Healthy Body Weight

  While about 80% of peri- and postmenopausal women have vasomotor symptoms (VMS), such as night sweats and hot flashes, it has been observed that higher body mass index (BMI) and body fat are associated with an increased risk of vasomotor symptoms. Thus, it is reasonable to speculate that weight loss may prevent VMS. In […]

Continue Reading · 0

In Brief: Why Exercise Helps with Menopausal Hot Flashes

Some, but not all, research studies have shown that exercise training can reduce the frequency of hot flushes and can improve other non-vasomotor symptoms including depression, anxiety, and insomnia.  Nevertheless, these studies have solely relied on subjective questionnaires as the primary outcome.  But if exercise makes you feel hot and sweaty, how does it help […]

Continue Reading · 0

Women Outperform Men on Tests of Cognitive Functioning — Until Menopause

Many women report cognitive difficulties — forgetfulness, distractibility, feeling foggy — as they enter into the menopause. Looking at sex-related differences in memory, Rentz and colleagues examined 212 men and women between the ages of 45 and 55 years.  Participants completed a battery of cognitive tests and underwent hormonal assessments. On all measures of cognitive […]

Continue Reading · 0

Treatment Challenges in Menopausal Women with Schizophrenia

Over the years there have been multiple reports indicating that women with schizophrenia may experience worsening of their symptoms as they transition into the menopause.  In addition, while schizophrenia typically has its onset in young adulthood, there is a second peak in women around menopause.  Researchers have postulated that falling estrogen levels may modulate dopaminergic […]

Continue Reading · 1