• maternal depression

    New Study Estimates the Astonishing Cost of Neglected Perinatal Mood and Anxiety Disorders in US Mothers

    A recently published article in the American Journal of Public Health has attributed a substantial financial cost to untreated perinatal mood and anxiety disorders among mothers. The study, conducted by researchers with the think [...]

    If We Are So Concerned About Maternal Mental Health, Why Don’t We Have More Mother-Baby Mental Health Programs? 

    The American College of Obstetricians and Gynecologists (ACOG) now recommends screening for perinatal depression, stating that “clinicians screen patients at least once during the perinatal period for depression and anxiety symptoms using a standard, [...]

    Prenatal Exposure to Maternal Depression and SSRIs Affect Network Connectivity, But in Different Ways

    While we have considerable data regarding the reproductive safety of antidepressants, including the selective serotonin reuptake inhibitors (SSRIs), most studies have focused on the prevalence of major malformations in children with prenatal exposure to [...]

    Maternal Depression, But Not Exposure to SSRIs, Associated with Worse Executive Functioning in Children  

    While we have considerable data on the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, most of this research focuses on the risk of congenital malformations in exposed children.  We have far less [...]

    Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

    In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]

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