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Tag Archives | hot flushes

You Asked: Can Modafinil (Provigil) be Used to Treat Menopausal Fatigue

Each year in the United States, the menopause transition is experienced by 1.5 million women.  With this change in the hormonal milieu comes troublesome symptoms, including vasomotor symptoms, decreased libido, insomnia, changes in mood, fatigue, and changes in cognitive functioning.   Fatigue is a common problem among middle-aged women; however, it has received less attention […]

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In Brief: Does Micronized Progesterone Relieve Perimenopausal Symptoms?

For decades, estrogen was used as a component of hormone replacement therapy to treat menopausal symptoms, including hot flashes, night sweats, and sleep disturbance; however, after several large, prospective studies (e.g., HERS, WHI) questioned the safety of long-term use of HRT, as well as its efficacy to prevent cardiovascular disease, many women have decided to […]

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Neurokinin-3 Receptor Antagonists: A Novel Approach to the Treatment of Menopausal Symptoms

Over the last few years, we have seen a number of articles suggesting that the burden of menopausal symptoms is probably greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause.  For most, the symptoms are manageable, but for a […]

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What Exactly Causes Hot Flashes in Menopausal Women? Researchers Look at Neurokinin B

Perimenopausal vasomotor symptoms are triggered by a fall in circulating levels of estrogen and other sex steroids. It has been hypothesized that thermoregulatory centres in the hypothalamus play a crucial role in mediating the hot flash response. However, exactly how do hormonal changes bring about these changes in the hypothalamus?  If we could understand this […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

Nonhormonal Management of Menopausal Vasomotor Symptoms: 2015 NAMS Position Statement

Since the Women’s Health Initiative (WHI) reported that the risks of menopausal hormone replacement therapy (HRT) outweighed its benefits, there has been a significant reduction in the use of HRT.  However, recent studies have suggested that many peri- and postmenopausal women experience significant symptoms for many years and that these symptoms have a marked impact […]

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Electroacupuncture Effective for Breast Cancer Treatment-Associated Hot Flashes

A recent study examined the effectiveness of electroacupuncture, in which small electric currents are applied to traditional acupuncture needles, in women with breast cancer treatment-associated hot flashes. 120 women with hot flashes were randomized to weekly electroacupuncture, once-daily gabapentin, sham acupuncture, or placebo for 8 weeks. Hot flashes were assessed using a daily self-reported hot […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

SSRIs for Vasomotor Symptoms and Bone Health

Recent research has indicated that selective serotonin reuptake inhibitors (SSRIs) may be an effective option for the treatment of vasomotor symptoms associated with menopause. However, it has been documented in some recent observational studies that SSRIs are associated with an increased risk of bone loss in older patients (2, 4). Since postmenopausal women are already […]

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New Research from the CWMH: Armodafinil for Menopause-Related Fatigue

Several recent articles indicate that the burden of menopausal symptoms is greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase.  For most, the symptoms are manageable, but for a sizeable subset of midlife women, these symptoms can negatively […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

New Research from the CWMH: Both Estradiol and Venlafaxine Improve Quality of Life in Perimenopausal Women with Hot Flashes

In healthy perimenopausal women with hot flashes, treatment with both estradiol and venlafaxine resulted in significantly greater improvement in quality of life, as compared to placebo. Estradiol had beneficial treatment effects on all domains of the MENQOL except for the psychosocial domain, whereas venlafaxine benefits were observed only in the psychosocial domain.   Caan B, LaCroix […]

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The Immense Burden of Menopausal Symptoms

Several recent articles suggest that the burden of menopausal symptoms is greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause phase.  For most, the symptoms are manageable, but for a sizeable subset of midlife women, these symptoms can negatively […]

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