• New Research from the CWMH: No Increase in Major Malformations in Children Prenatally Exposed to Aripiprazole

    Despite the increasing use of the newer atypical or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including psychotic disorders, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little [...]

    Are Clinicians Using the PLLR to Guide Prescribing During Pregnancy?

    In 2015, the U.S. Food and Drug Administration (FDA) proposed major revisions to prescription drug labeling -- the Pregnancy and Lactation Labeling Rule or PLLR -- in order to provide more accurate and helpful [...]

    Why Are We Still Using Valproic Acid (Depakote) in Women of Childbearing Age?

      There have long been concerns regarding the use of the anticonvulsant valproate (Depakote) during pregnancy.  First trimester use of valproate has been associated with a 3-5% risk of neural tube defects, as well as [...]

    New Research from the CWMH: Evaluating the Risk of Major Malformations in Children Prenatally Exposed to Atypical Antipsychotics

    Despite the increasing use of the newer “atypical” or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little data [...]

    November 2015 Roundup: Recent Publications in Reproductive Psychiatry

    It has been another busy month! Ruta Nonacs, MD PhD Antidepressants, pregnancy, and stigma: how we are failing mothers and babies. Osborne LM, Payne J. J Nerv Ment Dis. 2015 Mar;203(3):164-6. Do anxiety symptoms predict major depressive disorder in midlife [...]

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