New Research from the CWMH: No Increase in Major Malformations in Children with Prenatal Exposure to Olanzapine
No major malformations were associated with olanzapine exposure during the first trimester of pregnancy.
Prenatal Lithium Exposure: Neuroimaging Yields Reassuring Results
Functional MRI revealed no differences in brain structure of white matter integrity in lithium-exposed versus non-lithium-exposed children born to mothers with bipolar spectrum disorder.
Depression, Anxiety During Pregnancy Associated with Significant Increase in Adverse Perinatal Outcomes
Diagnosis of a mood or anxiety disorder during pregnancy was associated with a 3.5-fold increase in adverse perinatal outcomes.
Reassuring Data on Neurodevelopmental Outcomes in Children with Prenatal Exposure to Antipsychotic Medications
Two studies - one using neuropsychological assessments, another examining performance on standardized testing - show no association between prenatal antipsychotic exposure and neurodevelopmental outcomes.
No Link Between Prenatal Exposure to Antidepressants and Risk for ADHD in Offspring
Consistent with other studies, including a large meta-analysis, this study indicates no increased risk of ADHD in offspring following prenatal exposure to antidepressants.
Zuranolone: Novel, Rapid-Acting Antidepressant Awaits FDA Approval
A New Drug Application for zuranolone awaits FDA approval for the treatment of major depressive disorder (MDD) and postpartum depression (PPD).
Increased Risk of Preterm Birth in Veterans with PTSD
Largest studies to date demonstrate statistically significant risk of preterm birth among women with active PTSD.
Essential Reads: Prenatal Exposure to Benzodiazepines and Neurodevelopmental Outcomes
The largest study to date observes no increase in risk of autism or ADHD in children with prenatal exposure to benzodiazepines.
Essential Reads: Peer Support Interventions for Perinatal Depression
Peer support interventions can reduce the incidence of postpartum depression and the severity of depressive symptoms.
Maternal Adverse Childhood Experiences Linked to Changes in Neonatal Brain Development and Behavior
Maternal ACEs were associated with both newborn amygdala volume and subsequent infant negative emotionality.