Allopregnanolone is all over the place these days. We have seen several different allopregnanolone derivatives being used to treat postpartum depression (PPD). Last year, intravenous brexanolone (Zulresso) was approved by the FDA as the first [...]
Not infrequently we see women who ask about the possibility of oophorectomy (surgical removal of the ovaries) as a means of managing what appears to be a menstrually related mood disorder. While this is an [...]
Clinically we see that many women with major depressive disorder and bipolar disorder experience worsening of their symptoms prior to the onset of menses. We have less data on the impact of menstrual cycle on [...]
Chasteberry, the fruit of the chaste tree or Vitex agnus castus, has long been touted as a remedy for a range of reproductive problems, including premenstrual symptoms or PMS. Two recent publications have reviewed data [...]